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Anti-CDK11A / CDK11B Antibody

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产品名称: Anti-CDK11A / CDK11B Antibody
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Anti-CDK11A / CDK11B Antibody


Anti-CDK11A / CDK11B Antibody  的详细介绍
Name: Anti-CDK11A / CDK11B Antibody
See all CDK11A primary antibodies
Description: Rabbit polyclonal antibody to CDK11A / CDK11B
Specificity: The antibody detects endogenous levels of total CDK11A / CDK11B protein.
Applications: WB, IHC
Reactivity: Human, Mouse
Immunogen: Synthetic peptide corresponding to residues near the N terminal of human cyclin-dependent kinase 11A / B
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antigen affinity purification.
Concentration: 2.2mg / ml
Formulation: Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage: Store at -20?C
Function: Plays multiple roles in cell cycle progression, cytokinesis and apoptosis. Involved in pre-mRNA splicing in a kinase activity-dependent manner. Isoform 7 may act as a negative regulator of normal cell cycle progression.
Tissue Specificity: Expressed ubiquitously. Some evidence of isoform-specific tissue distribution.
Sequence Similarities: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
Post-Translational Modification: During FAS- or TNF-induced apoptosis, isoform SV9 is cleaved by caspases to produce p110C, a fragment that contains the C-terminal kinase domain.
Cellular Location: Cytoplasm. Nucleus.
Database Links:
  • Entrez Gene: 728642?Human
  • Entrez Gene: 12537?Mouse
  • Omim: 116951?Human
  • SwissProt: Q9UQ88?Human
  • SwissProt: P24788?Mouse
  • Unigene: 651228?Human
  • Unigene: 709182?Human
  • Unigene: 709182?Mouse
  • Synonyms:
  • CD11A_HUMAN Antibody
  • CDC2L2 Antibody
  • CDC2L3 Antibody
  • CDK11 Antibody
  • CDK11 / CDC2L2 Antibody
  • CDK11 p110 Antibody
  • CDK11 p46 Antibody
  • CDK11 p58 Antibody
  • CDK11A Antibody
  • Cell division cycle 2 like 2 (PITSLRE proteins) Antibody
  • Cell division cycle 2-like protein kinase 2 Antibody
  • Cell division protein kinase 11A Antibody
  • Cyclin-dependent kinase 11A Antibody
  • Galactosyltransferase-associated protein kinase p58/GTA Antibody
  • p58GTA Antibody
  • PITSLRE Antibody
  • PITSLRE B Antibody
  • PITSLRE protein kinase beta Antibody
  • PITSLRE serine/threonine-protein kinase CDC2L2 Antibody
  • PITSLREB Antibody
  • Information: Target information shown above is from the UniProt Consortium.
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