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Anti-CDC27 Antibody

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产品名称: Anti-CDC27 Antibody
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简单介绍

Anti-CDC27 Antibody


Anti-CDC27 Antibody  的详细介绍
Name: Anti-CDC27 Antibody
See all CDC27 primary antibodies
Description: Rabbit polyclonal antibody to CDC27
Specificity: The antibody detects endogenous levels of total CDC27 protein.
Applications: IHC
Reactivity: Human
Immunogen: Fusion protein corresponding to residues near the C terminal of human cell division cycle 27
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antigen affinity purification.
Concentration: 1.7mg / ml
Formulation: Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage: Store at -20?C
Function: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
Sequence Similarities: Belongs to the APC3/CDC27 family.
Post-Translational Modification: Phosphorylated. Phosphorylation on Ser-426 and Thr-446 occurs specifically during mitosis.
Cellular Location: Nucleus.
Database Links:
  • Entrez Gene: 996?Human
  • Omim: 116946?Human
  • SwissProt: P30260?Human
  • Unigene: 463295?Human
    		•
    Synonyms:
  • ANAPC3 Antibody
  • Anaphase Promoting Complex 3 Antibody
  • Anaphase promoting complex protein 3 Antibody
  • Anaphase Promoting Complex Subunit 3 Antibody
  • Anaphase-promoting complex subunit 3 Antibody
  • APC 3 Antibody
  • APC3 Antibody
  • Cdc 27 Antibody
  • Cdc27 Antibody
  • CDC27 homolog Antibody
  • CDC27Hs Antibody
  • CDC27_HUMAN Antibody
  • Cell Division Cycle 27 Antibody
  • Cell division cycle protein 27 homolog Antibody
  • D0S1430E Antibody
  • D17S978E Antibody
  • H NUC Antibody
  • H-NUC Antibody
  • HNUC Antibody
  • Nuc2 homolog Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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