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Anti-CDC23 Antibody

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产品名称: Anti-CDC23 Antibody
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简单介绍

Anti-CDC23 Antibody


Anti-CDC23 Antibody  的详细介绍
Name: Anti-CDC23 Antibody
See all CDC23 primary antibodies
Description: Rabbit polyclonal antibody to CDC23
Specificity: The antibody detects endogenous levels of total CDC23 protein.
Applications: WB, IHC
Reactivity: Human, Mouse
Immunogen: Synthetic peptide corresponding to a region derived from internal residues of human cell division cycle 23
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antigen affinity purification.
Concentration: 2.9mg / ml
Formulation: Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage: Store at -20?C
Function: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
Sequence Similarities: Belongs to the APC8/CDC23 family.
Post-Translational Modification: Phosphorylated. Phosphorylation on Thr-562 occurs specifically during mitosis.
Database Links:
  • Entrez Gene: 8697?Human
  • Entrez Gene: 52563?Mouse
  • Omim: 603462?Human
  • SwissProt: Q9UJX2?Human
  • SwissProt: Q8BGZ4?Mouse
  • Unigene: 73625?Human
  • Unigene: 196638?Mouse
  • Synonyms:
  • ANAPC8 Antibody
  • Anaphase promoting complex subunit 8 Antibody
  • Anaphase-promoting complex subunit 8 Antibody
  • Apc 8 Antibody
  • APC8 Antibody
  • Cdc 23 Antibody
  • Cdc23 Antibody
  • CDC23_HUMAN Antibody
  • cell division cycle 23 Antibody
  • Cell division cycle 23 homolog Antibody
  • Cell division cycle protein 23 Antibody
  • Cell division cycle protein 23 homolog Antibody
  • Cut23 Antibody
  • Cyclosome subunit 8 Antibody
  • Information: Target information shown above is from the UniProt Consortium.
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