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Anti-CD97 Antibody

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产品名称: Anti-CD97 Antibody
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Anti-CD97 Antibody


Anti-CD97 Antibody  的详细介绍
Name: Anti-CD97 Antibody
See all CD97 primary antibodies
Description: Mouse monoclonal (MEM-180) antibody to CD97 (FITC).
Specificity: The antibody MEM-180 recognizes a unique epitope on CD97, a 75-85 kDa surface glycoprotein of G-protein-coupled receptor family, expressed on activated B and T lymphocytes, monocytes/macrophages, dendritic cells and granulocytes.
Applications: FC, IP
Reactivity: Human
Immunogen: PHA-activated peripheral blood cells.
Host: Mouse
Clonality: Monoclonal
Clone: MEM-180
Isotype: IgG1
Conjugate: FITC
Product Form: Liquid
Formulation: Supplied in Phosphate Buffered Saline with 15mM Sodium Azide.
Storage: Store in the dark at 2-8°C. Avoid prolonged exposure to light.
Function: Receptor potentially involved in both adhesion and signaling processes early after leukocyte activation. Plays an essential role in leukocyte migration (By similarity).
Tissue Specificity: Broadly expressed, found on most hematopoietic cells, including activated lymphocytes, monocytes, macrophages, dendritic cells, and granulocytes. Expressed also abundantly by smooth muscle cells. Expressed in thyroid, colorectal, gastric, esophageal and pancreatic carcinomas too. Expression are increased under inflammatory conditions in the CNS of multiple sclerosis and in synovial tissue of patients with rheumatoid arthritis. Increased expression of CD97 in the synovium is accompanied by detectable levels of soluble CD97 in the synovial fluid.
Sequence Similarities: Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
Post-Translational Modification: Proteolytically cleaved into 2 subunits, an extracellular alpha subunit and a seven-transmembrane subunit.
Cellular Location: Cell membrane.
Database Links:
  • Entrez Gene: 976 Human
  • Omim: 601211 Human
  • SwissProt: P48960 Human
  • Unigene: 466039 Human
  • Synonyms:
  • ADGRE5 Antibody
  • Adhesion G protein-coupled receptor E5 Antibody
  • CD 97 Antibody
  • CD97 Antibody
  • CD97 antigen Antibody
  • CD97 antigen subunit beta Antibody
  • CD97 molecule Antibody
  • CD97_HUMAN Antibody
  • CD_antigen=CD97 Antibody
  • Leukocyte antigen CD97 Antibody
  • Seven span transmembrane protein Antibody
  • Seven transmembrane helix receptor Antibody
  • Seven transmembrane heterodimeric receptor associated with inflammation Antibody
  • TM7LN 1 Antibody
  • TM7LN1 Antibody
  • Information: Target information shown above is from the UniProt Consortium.
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