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Anti-CD74 Antibody

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产品名称: Anti-CD74 Antibody
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简单介绍

Anti-CD74 Antibody


Anti-CD74 Antibody  的详细介绍
Name: Anti-CD74 Antibody
See all CD74 primary antibodies
Description: Rabbit polyclonal antibody to CD74
Applications: WB, IHC
Reactivity: Human
Immunogen: Synthetic peptide contain a sequence corresponding to a region within amino acids 1 and 28 of CD74
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Purified by antigen-affinity chromatography.
Formulation: Supplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
Storage: Store at -20?C for long term preservation (recommended). Store at 4?C for short term use.
Function: Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal/lysosomal system where the antigen processing and binding of antigenic peptides to MHC class II takes place. Serves as cell surface receptor for the cytokine MIF.
Post-Translational Modification: N- and O-glycosylated. O-glycosylated with core 1 or possibly core 8 glycans.
Cellular Location: Cell membrane. Endoplasmic reticulum membrane. Golgi apparatus > trans-Golgi network. Endosome. Lysosome.

Transits through a number of intracellular compartments in the endocytic pathway. It can either undergo proteolysis or reach the cell membrane.
Database Links:
  • Entrez Gene: 972?Human
  • Omim: 142790?Human
  • SwissProt: P04233?Human
  • Unigene: 436568?Human
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    Synonyms:
  • CD 74 Antibody
  • CD74 Antibody
  • CD74 antigen Antibody
  • CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) Antibody
  • CD74 molecule Antibody
  • CD74 molecule, major histocompatibility complex, class II invariant chain Antibody
  • CLIP Antibody
  • DHLAG Antibody
  • Gamma chain of class II antigens Antibody
  • HG2A_HUMAN Antibody
  • HLA class II histocompatibility antigen gamma chain Antibody
  • HLA DR antigens associated invariant chain Antibody
  • HLA DR gamma Antibody
  • HLA-DR antigens-associated invariant chain Antibody
  • HLA-DR-gamma Antibody
  • HLADG Antibody
  • HLADR antigens associated invariant chain Antibody
  • Ia antigen associated invariant chain Antibody
  • Ia antigen-associated invariant chain Antibody
  • Ia associated invariant chain Antibody
  • Ia gamma Antibody
  • Ii Antibody
  • Invariant polypeptide of major histocompatibility complex class II antigen associated Antibody
  • la-gamma Antibody
  • Major histocompatibility complex class II invariant chain Antibody
  • MHC HLA DR gamma chain Antibody
  • MHC HLA-DR gamma chain Antibody
  • p33 Antibody
  • p35 Antibody
  • Protein 41 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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