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Anti-CD68 Antibody

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产品名称: Anti-CD68 Antibody
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简单介绍

Anti-CD68 Antibody


Anti-CD68 Antibody  的详细介绍
Name: Anti-CD68 Antibody
See all CD68 primary antibodies
Description: Rabbit polyclonal antibody to CD68
Specificity: The antibody detects endogenous levels of total CD68 protein.
Applications: IHC
Reactivity: Human
Immunogen: Synthetic peptide corresponding to a region derived from internal residues of human CD68 molecule
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antigen affinity purification.
Concentration: 2.2mg / ml
Formulation: Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage: Store at -20?C
Function: Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.
Tissue Specificity: Highly expressed by blood monocytes and tissue macrophages. Also expressed in lymphocytes, fibroblasts and endothelial cells. Expressed in many tumor cell lines which could allow them to attach to selectins on vascular endothelium, facilitating their dissemination to secondary sites.
Sequence Similarities: Belongs to the LAMP family.
Post-Translational Modification: N- and O-glycosylated.
Cellular Location: Cell membrane.
Database Links:
  • Entrez Gene: 968?Human
  • Omim: 153634?Human
  • SwissProt: P34810?Human
  • Unigene: 647419?Human
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    Synonyms:
  • CD 68 Antibody
  • CD68 Antibody
  • CD68 antigen Antibody
  • CD68 molecule Antibody
  • CD68_HUMAN Antibody
  • DKFZp686M18236 Antibody
  • gp11 Antibody
  • Gp110 Antibody
  • LAMP4 Antibody
  • MACROPHAGE ANTIGEN CD68 Antibody
  • Macrophage antigen CD68 (microsialin) Antibody
  • Macrosialin Antibody
  • SCARD1 Antibody
  • Scavenger receptor class D member 1 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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