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Anti-CD66c / d Antibody

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产品名称: Anti-CD66c / d Antibody
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Anti-CD66c / d Antibody


Anti-CD66c / d Antibody  的详细介绍
Name: Anti-CD66c / d Antibody
See all CD66c primary antibodies
Description: Rabbit polyclonal antibody to CD66c / d
Specificity: CD66c / d Polyclonal Antibody detects endogenous levels of CD66c / d protein.
Applications: WB, ELISA
Reactivity: Human
Immunogen: Synthesized peptide derived from the Internal region of human CD66c / d.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1mg / ml
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage: Store at -20˚C / 1 year
Function: Major granulocyte receptor mediating recognition and efficient opsonin-independent phagocytosis of CEACAM-binding microorganisms, including Neissiria, Moxarella and Haemophilus species, thus playing an important role in the clearance of pathogens by the innate immune system. Responsible for RAC1 stimulation in the course of pathogen phagocytosis.
Tissue Specificity: CGM1a, the predominant CGM1 transcript, is granulocyte-specific. Not detected out of the granulocytic lineage, such as monocytes, lymphocytes, spleen, testis, colon, brain, liver, pancreas, thymus, ovary, placenta, skeletal muscle, prostate, small intestine, heart, lung and kidney.
Sequence Similarities: Belongs to the immunoglobulin superfamily. CEA family.
Post-Translational Modification: Tyrosine-phosphorylated in response to microbial binding. Tyr-230 and Tyr-241 are both required for phosphorylation to be detected.
Cellular Location: Membrane.
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