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Anti-CD47 Antibody

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产品名称: Anti-CD47 Antibody
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简单介绍

Anti-CD47 Antibody


Anti-CD47 Antibody  的详细介绍
Name: Anti-CD47 Antibody
See all CD47 primary antibodies
Description: Rabbit polyclonal antibody to CD47.
Applications: WB, IHC, IF
Dilutions: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:200.
Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein of human CD47.
Protein Length: 323(305)
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Affinity purification.
Product Form: Liquid
Formulation: Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection.
Tissue Specificity: Very broadly distributed on normal ***** tissues, as well as ovarian tumors, being especially abundant in some epithelia and the brain.
Cellular Location: Cell membrane.
Database Links:
  • Entrez Gene: 961?Human
  • Entrez Gene: 16423?Mouse
  • Entrez Gene: 29364?Rat
  • Omim: 601028?Human
  • SwissProt: Q08722?Human
  • SwissProt: Q61735?Mouse
  • SwissProt: P97829?Rat
  • Unigene: 446414?Human
  • Unigene: 31752?Mouse
  • Unigene: 390865?Mouse
  • Unigene: 7409?Rat
    		•
    Synonyms:
  • Antigen identified by monoclonal Antibody
  • Antigenic surface determinant protein OA3 Antibody
  • CD 47 Antibody
  • CD47 Antibody
  • CD47 antigen Antibody
  • CD47 antigen (Rh-related antigen, integrin-associated signal transducer) Antibody
  • CD47 glycoprotein Antibody
  • CD47 molecule Antibody
  • CD47_HUMAN Antibody
  • IAP Antibody
  • Integrin Associated Protein Antibody
  • Integrin associated signal transducer Antibody
  • Integrin-associated protein Antibody
  • Leukocyte surface antigen CD47 Antibody
  • MER 6 Antibody
  • MER6 Antibody
  • OA 3 Antibody
  • OA3 Antibody
  • OTTHUMP00000041152 Antibody
  • OTTHUMP00000041153 Antibody
  • Protein MER6 Antibody
  • Rh related antigen Antibody
  • Surface antigen identified by monoclonal Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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