产品资料

Anti-CD44 Antibody

如果您对该产品感兴趣的话,可以
产品名称: Anti-CD44 Antibody
产品型号:
产品展商: 其它品牌
产品文档: 无相关文档

简单介绍

Anti-CD44 Antibody


Anti-CD44 Antibody  的详细介绍
Name: Anti-CD44 Antibody
See all CD44 primary antibodies
Description: Rabbit polyclonal antibody to CD44
Specificity: CD44 Polyclonal Antibody detects endogenous levels of CD44 protein.
Applications: WB, ELISA
Reactivity: Human, Mouse, Rat
Immunogen: Synthesized peptide derived from human CD44 around the non-phosphorylation site of S706.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1mg / ml
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage: Store at -20˚C / 1 year
Function: Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. In cancer cells, may play an important role in invadopodia formation. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events. Receptor for LGALS9; the interaction enhances binding of SMAD3 to the FOXP3 promoter, leading to up-regulation of FOXP3 expression and increased induced regulatory T (iTreg) cell stability and suppressive function (By similarity).
Tissue Specificity: Isoform 10 (epithelial isoform) is expressed by cells of epithelium and highly expressed by carcinomas. Expression is repressed in neuroblastoma cells.
Post-Translational Modification: Proteolytically cleaved in the extracellular matrix by specific proteinases (possibly MMPs) in several cell lines and tumors.
Cellular Location: Cell membrane.

Colocalizes with actin in membrane protrusions at wounding edges.
Database Links:
  • Entrez Gene: 960 Human
  • Entrez Gene: 12505 Mouse
  • Entrez Gene: 25406 Rat
  • Omim: 107269 Human
  • SwissProt: P16070 Human
  • SwissProt: P15379 Mouse
  • SwissProt: P26051 Rat
  • Unigene: 502328 Human
  • Unigene: 423621 Mouse
  • Unigene: 1120 Rat
    		•
    Synonyms:
  • LHR Antibody
  • BA-1 Antibody
  • CD 44 Antibody
  • CD44 Antibody
  • CD44 antigen Antibody
  • CD44 molecule Antibody
  • CD44 molecule (Indian blood group) Antibody
  • CD44_HUMAN Antibody
  • CDw44 Antibody
  • Cell surface glycoprotein CD44 Antibody
  • chondroitin sulfate proteoglycan 8 Antibody
  • CSPG8 Antibody
  • ECMR-III Antibody
  • Epican Antibody
  • Extracellular matrix receptor III Antibody
  • GP90 lymphocyte homing/adhesion receptor Antibody
  • HCELL Antibody
  • hematopoietic cell E- and L-selectin ligand Antibody
  • Heparan sulfate proteoglycan Antibody
  • Hermes antigen Antibody
  • homing function and Indian blood group system Antibody
  • HSA Antibody
  • HUTCH-I Antibody
  • HUTCH1 Antibody
  • Hyaluronate receptor Antibody
  • IN Antibody
  • INLU-related p80 Glycoprotein Antibody
  • MC56 Antibody
  • MDU2 Antibody
  • MDU3 Antibody
  • MGC10468 Antibody
  • MIC4 Antibody
  • MUTCH1 Antibody
  • PGP-1 Antibody
  • PGP-I Antibody
  • PGP1 Antibody
  • Phagocytic glycoprotein 1 Antibody
  • Phagocytic glycoprotein I Antibody
  • Soluble CD44 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
    产品留言
    标题
    联系人
    联系电话
    内容
    验证码
    点击换一张
    注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
    2.如有必要,请您留下您的详细联系方式!

    沪公网安备 31011202007337号