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Anti-CD43 Antibody

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产品名称: Anti-CD43 Antibody
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简单介绍

Anti-CD43 Antibody


Anti-CD43 Antibody  的详细介绍
Name: Anti-CD43 Antibody
See all CD43 primary antibodies
Description: Mouse monoclonal (MEM-59) antibody to CD43 (Biotin).
Specificity: The antibody MEM-59 recognizes neuraminidase-sensitive epitope on CD43 (Leukosialin), a 95-135 kDa type I transmembrane glycoprotein (mucin-type) which is involved in lymphocyte activation. CD43 is expressed by platelets and at high levels on the surface of all leukocytes; it is negative on resting B lymphocytes and erythrocytes.
Applications: FC, IP, WB, IHC-P, FUNC
Reactivity: Human
Immunogen: Human T lymphocytes.
Host: Mouse
Clonality: Monoclonal
Clone: MEM-59
Isotype: IgG1
Conjugate: Biotin
Concentration: 1 mg/ml
Product Form: Liquid
Formulation: Supplied in Tris Buffered Saline, pH 8.0, with 15mM Sodium Azide.
Storage: Store at 2-8°C.
Function: One of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochemical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter-receptor for SN/Siglec-1 (By similarity). During T-cell activation is actively removed from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response (By similarity).
Tissue Specificity: Cell surface of thymocytes, T-lymphocytes, neutrophils, plasma cells and myelomas.
Post-Translational Modification: Glycosylated; has a high content of sialic acid and O-linked carbohydrate structures.
Cellular Location: Membrane.
Database Links:
  • Entrez Gene: 6693?Human
  • Omim: 182160?Human
  • SwissProt: P16150?Human
  • Unigene: 632188?Human
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    Synonyms:
  • CD 43 Antibody
  • CD43 Antibody
  • CD43 antigen Antibody
  • Galactoglycoprotein Antibody
  • GALGP Antibody
  • GPL 115 Antibody
  • GPL115 Antibody
  • Human gene for sialophorin Antibody
  • Leucocyte sialoglycoprotein Antibody
  • Leukocyte large sialoglycoprotein Antibody
  • Leukocyte sialoglycoprotein Antibody
  • Leukosialin Antibody
  • LEUK_HUMAN Antibody
  • LSN Antibody
  • Ly-48 Antibody
  • Sialophorin Antibody
  • sialophorin (gpL115, leukosialin, CD43) Antibody
  • Spn Antibody
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    Information: Target information shown above is from the UniProt Consortium.
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