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Anti-CD3-δ Antibody

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产品名称: Anti-CD3-δ Antibody
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Anti-CD3-δ Antibody


Anti-CD3-δ Antibody  的详细介绍
Name: Anti-CD3-δ Antibody
See all CD3-δ primary antibodies
Description: Rabbit polyclonal antibody to CD3-δ
Specificity: CD3-δ pAb detects endogenous levels of CD3-δ protein.
Applications: WB, IHC
Reactivity: Human
Immunogen: Recombinant full length Human CD3-δ.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Molecular Weight: ~ 24 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form: 1mg/ml in PBS?with?0.1%?Sodium?Azide,?50%?Glycerol.
Function: The CD3 complex mediates signal transduction.
Involvement in Disease: Severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive: A form of severe combined immunodeficiency (SCID), a genetically and clinically heterogeneous group of rare congenital disorders characterized by impairment of both humoral and cell-mediated immunity, leukopenia, and low or absent antibody levels. Patients present in infancy recurrent, persistent infections by opportunistic organisms. The common characteristic of all types of SCID is absence of T-cell-mediated cellular immunity due to a defect in T-cell development.

Immunodeficiency 19: An autosomal recessive form of severe combined immunodeficiency characterized by onset in early infancy of recurrent bacterial, viral, and fungal infections. Patients usually have chronic diarrhea, recurrent respiratory infections, and failure to thrive. Immunologic work-up shows a T-cell negative, B-cell positive, NK-cell positive phenotype.
Cellular Location: Membrane.
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