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Anti-CD274 Antibody

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产品名称: Anti-CD274 Antibody
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简单介绍

Anti-CD274 Antibody


Anti-CD274 Antibody  的详细介绍
Name: Anti-CD274 Antibody
See all CD274 primary antibodies
Description: Rabbit polyclonal antibody to CD274
Specificity: CD274 pAb detects endogenous levels of CD274 protein.
Applications: WB, IHC
Reactivity: Human
Immunogen: Recombinant full length Human CD274.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Molecular Weight: ~ 33 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Function: Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.
Tissue Specificity: Highly expressed in the heart, skeletal muscle, placenta and lung. Weakly expressed in the thymus, spleen, kidney and liver. Expressed on activated T- and B-cells, dendritic cells, keratinocytes and monocytes.
Sequence Similarities: Belongs to the immunoglobulin superfamily. BTN/MOG family.
Cellular Location: Cell membrane.
Database Links:
  • Entrez Gene: 29126?Human
  • Omim: 605402?Human
  • SwissProt: Q9NZQ7?Human
  • Unigene: 521989?Human
    		•
    Synonyms:
  • B7 H Antibody
  • B7 H1 Antibody
  • B7 homolog 1 Antibody
  • B7-H1 Antibody
  • B7H Antibody
  • B7H1 Antibody
  • CD 274 Antibody
  • CD274 Antibody
  • CD274 antigen Antibody
  • CD274 molecule Antibody
  • MGC142294 Antibody
  • MGC142296 Antibody
  • OTTHUMP00000021029 Antibody
  • PD L1 Antibody
  • PD-L1 Antibody
  • PD1L1_HUMAN Antibody
  • PDCD1 ligand 1 Antibody
  • PDCD1L1 Antibody
  • PDCD1LG1 Antibody
  • PDL 1 Antibody
  • PDL1 Antibody
  • Programmed cell death 1 ligand 1 Antibody
  • Programmed death ligand 1 Antibody
  • RGD1566211 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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