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Anti-CD27 Antibody

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Anti-CD27 Antibody


Anti-CD27 Antibody  的详细介绍
Name: Anti-CD27 Antibody
See all CD27 primary antibodies
Description: Mouse monoclonal (LT27) antibody to CD27 (PE).
Specificity: The antibody LT27 reacts with CD27 (T14), a 50-55 kDa type I transmembrane glycoprotein (member of the TNF-receptor superfamily) expressed on medullary thymocytes, peripheral T lymphocytes, some B lymphocytes and NK cells.
Applications: FC
Reactivity: Human
Immunogen: Human peripheral blood lymphocytes.
Host: Mouse
Clonality: Monoclonal
Clone: LT27
Isotype: IgG2a
Conjugate: PE
Purification: Size exclusion chromatography.
Product Form: Liquid
Formulation: Supplied in Phosphate Buffered Saline with 15mM Sodium Azide.
Storage: Store in the dark at 2-8°C. Avoid prolonged exposure to light.
Function: Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1.
Tissue Specificity: Found in most T-lymphocytes.
Involvement in Disease: Lymphoproliferative syndrome 2: An autosomal recessive immunodeficiency disorder associated with persistent symptomatic EBV viremia, hypogammaglobulinemia, and impaired T-cell-dependent B-cell responses and T-cell dysfunction. The phenotype is highly variable, ranging from asymptomatic borderline-low hypogammaglobulinemia, to a full-blown symptomatic systemic inflammatory response with life-threatening EBV-related complications, including hemophagocytic lymphohistiocytosis, a lymphoproliferative disorder, and malignant lymphoma requiring stem cell transplantation.
Post-Translational Modification: Phosphorylated.
Cellular Location: Membrane.
Database Links:
  • Entrez Gene: 939 Human
  • Omim: 186711 Human
  • SwissProt: P26842 Human
  • Unigene: 355307 Human
    		•
    Synonyms:
  • CD 27 Antibody
  • CD27 Antibody
  • CD27 antigen Antibody
  • CD27 molecule Antibody
  • CD27L receptor Antibody
  • CD27_HUMAN Antibody
  • LPFS2 Antibody
  • MGC20393 Antibody
  • OTTHUMP00000238557 Antibody
  • S152 Antibody
  • T cell activation antigen CD27 Antibody
  • T cell antivation antigen S152 Antibody
  • T-cell activation antigen CD27 Antibody
  • T14 Antibody
  • TNFRSF 7 Antibody
  • TNFRSF7 Antibody
  • TNFSF7 Antibody
  • Tp 55 Antibody
  • Tp55 Antibody
  • Tumor necrosis factor receptor superfamily member 7 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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