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Anti-CD253 Antibody

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产品名称: Anti-CD253 Antibody
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Anti-CD253 Antibody


Anti-CD253 Antibody  的详细介绍
Name: Anti-CD253 Antibody
See all CD253 primary antibodies
Description: Rabbit polyclonal antibody to CD253
Specificity: The antibody detects endogenous levels of total CD253 protein.
Applications: WB, IF
Reactivity: Human
Immunogen: Synthesized peptide derived from internal of human CD253.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1.0mg / ml
Formulation: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage: Store at -20˚C
Function: Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis.
Tissue Specificity: Widespread; most predominant in spleen, lung and prostate.
Sequence Similarities: Belongs to the tumor necrosis factor family.
Post-Translational Modification: Tyrosine phosphorylated by PKDCC/VLK.
Cellular Location: Membrane.
Database Links:
  • Entrez Gene: 8743 Human
  • Omim: 603598 Human
  • SwissProt: P50591 Human
  • Unigene: 478275 Human
    		•
    Synonyms:
  • Apo 2 ligand Antibody
  • APO 2L Antibody
  • Apo-2 ligand Antibody
  • Apo-2L Antibody
  • APO2L Antibody
  • CD253 Antibody
  • CD253 antigen Antibody
  • Chemokine tumor necrosis factor ligand superfamily member 10 Antibody
  • Protein TRAIL Antibody
  • TL2 Antibody
  • TNF Related Apoptosis Inducing Ligand Antibody
  • TNF related apoptosis inducing ligand TRAIL Antibody
  • TNF-related apoptosis-inducing ligand Antibody
  • TNF10_HUMAN Antibody
  • TNFSF10 Antibody
  • TRAIL Antibody
  • Tumor necrosis factor (ligand) family member 10 Antibody
  • Tumor Necrosis Factor (ligand) Superfamily Member 10 Antibody
  • Tumor necrosis factor apoptosis inducing ligand splice variant delta Antibody
  • Tumor necrosis factor ligand superfamily member 10 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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