产品资料

Anti-CD24 Antibody

如果您对该产品感兴趣的话,可以
产品名称: Anti-CD24 Antibody
产品型号:
产品展商: 其它品牌
产品文档: 无相关文档

简单介绍

Anti-CD24 Antibody


Anti-CD24 Antibody  的详细介绍
Name: Anti-CD24 Antibody
See all CD24 primary antibodies
Description: Rabbit polyclonal antibody to CD24
Specificity: The antibody detects endogenous levels of total CD24 protein.
Applications: IHC
Reactivity: Human
Immunogen: Synthetic peptide corresponding to a region derived from internal residues of human CD24 molecule
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antigen affinity purification.
Concentration: 1.8mg / ml
Formulation: Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage: Store at -20?C
Function: Modulates B-cell activation responses. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells.
Tissue Specificity: B-cells. Expressed in a number of B-cell lines including P32/ISH and Namalwa. Expressed in erythroleukemia cell and small cell lung carcinoma cell lines. Also expressed on the surface of T-cells.
Involvement in Disease: Multiple sclerosis: A multifactorial, inflammatory, demyelinating disease of the central nervous system. Sclerotic lesions are characterized by perivascular infiltration of monocytes and lymphocytes and appear as indurated areas in pathologic specimens (sclerosis in plaques). The pathological mechanism is regarded as an autoimmune attack of the myelin sheath, mediated by both cellular and humoral immunity. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia and bladder dysfunction. Genetic and environmental factors influence susceptibility to the disease.
Sequence Similarities: Belongs to the CD24 family.
Post-Translational Modification: Extensively O-glycosylated.
Cellular Location: Cell membrane.
Database Links:
  • Entrez Gene: 100133941?Human
  • Omim: 600074?Human
  • SwissProt: P25063?Human
  • Unigene: 644105?Human
  • Unigene: 721443?Human
    		•
    Synonyms:
  • CD 24 Antibody
  • CD24 Antibody
  • CD24 antigen Antibody
  • CD24 antigen (small cell lung carcinoma cluster 4 antigen) Antibody
  • CD24 molecule Antibody
  • CD24A Antibody
  • CD24_HUMAN Antibody
  • FLJ22950 Antibody
  • FLJ43543 Antibody
  • GPI linked surface mucin Antibody
  • Heat stable antigen Antibody
  • HSA Antibody
  • MGC75043 Antibody
  • Nectadrin Antibody
  • Signal transducer CD24 Antibody
  • Small cell lung carcinoma cluster 4 antigen Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
    产品留言
    标题
    联系人
    联系电话
    内容
    验证码
    点击换一张
    注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
    2.如有必要,请您留下您的详细联系方式!

    沪公网安备 31011202007337号