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Anti-CD200R1 Antibody

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产品名称: Anti-CD200R1 Antibody
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简单介绍

Anti-CD200R1 Antibody


Anti-CD200R1 Antibody  的详细介绍
Name: Anti-CD200R1 Antibody
See all CD200R1 primary antibodies
Description: Rabbit polyclonal antibody to CD200R1
Specificity: The antibody detects endogenous levels of total CD200R1 protein.
Applications: IHC
Reactivity: Human
Immunogen: Fusion protein corresponding to a region derived from internal residues of human CD200 receptor 1
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antigen affinity purification.
Concentration: 3mg / ml
Formulation: Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage: Store at -20?C
Function: Inhibitory receptor for the CD200/OX2 cell surface glycoprotein. Limits inflammation by inhibiting the expression of proinflammatory molecules including TNF-alpha, interferons, and inducible nitric oxide synthase (iNOS) in response to selected stimuli. Also binds to HHV-8 K14 viral CD200 homolog with identical affinity and kinetics as the host CD200.
Tissue Specificity: Expressed in granulocytes, monocytes, most T-cells, neutrophils, basophils and a subset of NK, NKT and B-cells (at protein level). Expressed in bone marrow, lymph nodes, spleen, lung, liver, spinal cord, kidney. Expressed in monocyte-derived dendritic and mast cells.
Sequence Similarities: Belongs to the CD200R family.
Post-Translational Modification: The mature form of isoform 2 and/or isoform 4 starts at sequence position 27 of the corresponding isoform.
Cellular Location: Cell membrane.
Database Links:
  • Entrez Gene: 131450?Human
  • Omim: 607546?Human
  • SwissProt: Q8TD46?Human
  • Unigene: 309158?Human
    		•
    Synonyms:
  • CD 200R Antibody
  • CD200 cell surface glycoprotein receptor Antibody
  • CD200 receptor 1 Antibody
  • CD200R Antibody
  • Cd200r1 Antibody
  • Cell surface glycoprotein CD200 receptor 1 Antibody
  • Cell surface glycoprotein OX2 receptor Antibody
  • Cell surface glycoprotein OX2 receptor 1 Antibody
  • cell surface glycoprotein receptor CD200 Antibody
  • CRTR 2 Antibody
  • CRTR2 Antibody
  • HCRTR2 Antibody
  • MO2R1_HUMAN Antibody
  • MOX2 receptor Antibody
  • MOX2R Antibody
  • OX2R Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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