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Anti-CD101 Antibody

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产品名称: Anti-CD101 Antibody
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简单介绍

Anti-CD101 Antibody


Anti-CD101 Antibody  的详细介绍
Name: Anti-CD101 Antibody
See all CD101 primary antibodies
Description: Rabbit polyclonal antibody to CD101
Specificity: CD101 Polyclonal Antibody detects endogenous levels of CD101 protein.
Applications: WB, ELISA
Reactivity: Human
Immunogen: Synthesized peptide derived from the Internal region of human CD101.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1mg / ml
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage: Store at -20˚C / 1 year
Function: Plays a role as inhibitor of T-cells proliferation induced by CD3. Inhibits expression of IL2RA on activated T-cells and secretion of IL2. Inhibits tyrosine kinases that are required for IL2 production and cellular proliferation. Inhibits phospholipase C-gamma-1/PLCG1 phosphorylation and subsequent CD3-induced changes in intracellular free calcium. Prevents nuclear translocation of nuclear factor of activated T-cell to the nucleus. Plays a role in the inhibition of T-cell proliferation via IL10 secretion by cutaneous dendritic cells. May be a marker of CD4(+) CD56(+) leukemic tumor cells.
Tissue Specificity: Expressed in lung, thymus and small intestine. Detected in cutaneous dendritic cells, activated T-cells, monocytes and granulocytes as well as with epithelial cells with dendritic morphology. Expressed in some leukemic cells, the CD4(+) CD56(+) blastic tumor cells, as well as in Langerhans cells from LCH (Langerhans cell histiocytosis) patients.
Post-Translational Modification: N-glycosylated.
Cellular Location: Membrane.
Database Links:
  • Entrez Gene: 9398 Human
  • Omim: 604516 Human
  • SwissProt: Q93033 Human
  • Unigene: 654598 Human
  • Unigene: 74115 Human
    		•
    Synonyms:
  • CD101 Antibody
  • CD101 molecule Antibody
  • cell surface glycoprotein V7 Antibody
  • EWI-101 Antibody
  • glu-Trp-Ile EWI motif-containing protein 101 Antibody
  • IGSF2 Antibody
  • Immunoglobulin superfamily member 2 Antibody
  • Leukocyte surface protein Antibody
  • V7 Antibody
  • V7 LSB Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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