产品资料

Anti-CCR5 Antibody

如果您对该产品感兴趣的话,可以
产品名称: Anti-CCR5 Antibody
产品型号:
产品展商: 其它品牌
产品文档: 无相关文档

简单介绍

Anti-CCR5 Antibody


Anti-CCR5 Antibody  的详细介绍
Name: Anti-CCR5 Antibody
See all CCR5 primary antibodies
Description: Rabbit polyclonal antibody to CCR5
Applications: ELISA, IHC, IP, WB
Dilutions: DB: 1:10,000; ELISA: 1:10,000; Western Blot: 1:500
Reactivity: Human, Monkey, Rat
Immunogen: Synthetic peptide taken within amino acid region 1-50 on human CCR5 protein.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Concentration: 0.64-0.70 μg/μl in antibody stabilization buffer
Storage: -20?C for long term storage
Function: Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates.
Tissue Specificity: Highly expressed in spleen, thymus, in the myeloid cell line THP-1, in the promyeloblastic cell line KG-1a and on CD4+ and CD8+ T-cells. Medium levels in peripheral blood leukocytes and in small intestine. Low levels in ovary and lung.
Involvement in Disease: Diabetes mellitus, insulin-dependent, 22: A multifactorial disorder of glucose homeostasis that is characterized by susceptibility to ketoacidosis in the absence of insulin therapy. Clinical features are polydipsia, polyphagia and polyuria which result from hyperglycemia-induced osmotic diuresis and secondary thirst. These derangements result in long-term complications that affect the eyes, kidneys, nerves, and blood vessels.
Sequence Similarities: Belongs to the G-protein coupled receptor 1 family.
Post-Translational Modification: Sulfated on at least 2 of the N-terminal tyrosines. Sulfation contributes to the efficiency of HIV-1 entry and is required for efficient binding of the chemokines, CCL3 and CCL4.
Cellular Location: Cell membrane.
Database Links:
  • Entrez Gene: 1234?Human
  • Entrez Gene: 117029?Rat
  • Omim: 601373?Human
  • SwissProt: P51681?Human
  • SwissProt: O08556?Rat
  • Unigene: 450802?Human
  • Unigene: 10736?Rat
    		•
    Synonyms:
  • AM4 7 Antibody
  • C C chemokine receptor type 5 Antibody
  • C C CKR 5 Antibody
  • C-C chemokine receptor type 5 Antibody
  • C-C CKR-5 Antibody
  • C-C motif chemokine receptor 5 A159A Antibody
  • CC Chemokine Receptor 5 Antibody
  • CC Chemokine Receptor Type 5 Antibody
  • CC CKR 5 Antibody
  • CC-CKR-5 Antibody
  • CCCKR 5 Antibody
  • CCCKR5 Antibody
  • CCR 5 Antibody
  • CCR-5 Antibody
  • CCR5 Antibody
  • CCR5 chemokine (C C motif) receptor 5 Antibody
  • CCR5_HUMAN Antibody
  • CD 195 Antibody
  • CD195 Antibody
  • CD195 Antigen Antibody
  • Chemokine C C motif receptor 5 Antibody
  • Chemokine receptor CCR5 Antibody
  • CHEMR13 Antibody
  • CKR 5 Antibody
  • CKR5 Antibody
  • CMKBR 5 Antibody
  • CMKBR5 Antibody
  • FLJ78003 Antibody
  • HIV 1 Fusion Coreceptor Antibody
  • HIV-1 fusion coreceptor Antibody
  • HIV1 fusion coreceptor Antibody
  • IDDM22 Antibody
  • MIP-1 alpha receptor Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
    产品留言
    标题
    联系人
    联系电话
    内容
    验证码
    点击换一张
    注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
    2.如有必要,请您留下您的详细联系方式!

    沪公网安备 31011202007337号