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Anti-CCNE2 Antibody

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产品名称: Anti-CCNE2 Antibody
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简单介绍

Anti-CCNE2 Antibody


Anti-CCNE2 Antibody  的详细介绍
Name: Anti-CCNE2 Antibody
See all CCNE2 primary antibodies
Description: Rabbit polyclonal antibody to CCNE2
Specificity: The antibody detects endogenous levels of total CCNE2 protein.
Applications: IHC
Reactivity: Human
Immunogen: Synthetic peptide corresponding to a region derived from internal residues of human cyclin E2
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antigen affinity purification.
Concentration: 2.4mg / ml
Formulation: Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage: Store at -20?C
Function: Essential for the control of the cell cycle at the late G1 and early S phase.
Tissue Specificity: According to PubMed:9858585, highest levels of expression in ***** testis, thymus and brain. Lower levels in placenta, spleen and colon. Consistently elevated levels in tumor-derived cells compared to non-transformed proliferating cells. According to PubMed:9840927: low levels in thymus, prostate, brain, skeletal muscle, and kidney. Elevated levels in lung. According to PubMed:9840943 highly expressed in testis, placenta, thymus and brain. In a lesser extent in small intestine and colon.
Sequence Similarities: Belongs to the cyclin family. Cyclin E subfamily.
Post-Translational Modification: Phosphorylation by CDK2 triggers its release from CDK2 and degradation via the ubiquitin proteasome pathway.
Cellular Location: Nucleus.
Database Links:
  • Entrez Gene: 9134?Human
  • Omim: 603775?Human
  • SwissProt: O96020?Human
  • Unigene: 567387?Human
    		•
    Synonyms:
  • CCN E2 Antibody
  • CCNE 2 Antibody
  • CCNE2 Antibody
  • CCNE2 protein Antibody
  • CYC E2 Antibody
  • CYCE 2 Antibody
  • CYCE2 Antibody
  • Cyclin E2 Antibody
  • CyclinE2 Antibody
  • G1/S specific cyclin E2 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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