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Anti-CCL22 Antibody

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产品名称: Anti-CCL22 Antibody
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简单介绍

Anti-CCL22 Antibody


Anti-CCL22 Antibody  的详细介绍
Name: Anti-CCL22 Antibody
See all CCL22 primary antibodies
Description: Rabbit polyclonal antibody to CCL22
Specificity: CCL22 pAb detects endogenous levels of CCL22 protein.
Applications: WB, IHC
Reactivity: Human
Immunogen: Recombinant full length Human CCL22.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Molecular Weight: ~ 10 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form: 1mg/ml in PBS?with?0.1%?Sodium?Azide,?50%?Glycerol.
Function: May play a role in the trafficking of activated/effector T-lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. Chemotactic for monocytes, dendritic cells and natural killer cells. Mild chemoattractant for primary activated T-lymphocytes and a potent chemoattractant for chronically activated T-lymphocytes but has no chemoattractant activity for neutrophils, eosinophils, and resting T-lymphocytes. Binds to CCR4. Processed forms MDC(3-69), MDC(5-69) and MDC(7-69) seem not be active.
Tissue Specificity: Highly expressed in macrophage and in monocyte-derived dendritic cells, and thymus. Also found in lymph node, appendix, activated monocytes, resting and activated macrophages. Lower expression in lung and spleen. Very weak expression in small intestine. In lymph node expressed in a mature subset of Langerhans' cells (CD1a+ and CD83+). Expressed in Langerhans' cell histiocytosis but not in dermatopathic lymphadenopathy. Expressed in atopic dermatitis, allergic contact dermatitis skin, and psoriasis, in both the epidermis and dermis.
Sequence Similarities: Belongs to the intercrine beta (chemokine CC) family.
Post-Translational Modification: The N-terminal processed forms MDC(3-69), MDC(5-69) and MDC(7-69) are produced by proteolytic cleavage after secretion from monocyte derived dendrocytes.
Cellular Location: Secreted.
Database Links:
  • Entrez Gene: 6367?Human
  • Omim: 602957?Human
  • SwissProt: O00626?Human
  • Unigene: 534347?Human
    		•
    Synonyms:
  • A 152E5.1 Antibody
  • A-152E5.1 Antibody
  • ABCD 1 Antibody
  • ABCD1 Antibody
  • C C motif chemokine 22 Antibody
  • C-C motif chemokine 22 Antibody
  • CC chemokine STCP 1 Antibody
  • CC chemokine STCP-1 Antibody
  • ccl 22 Antibody
  • Ccl22 Antibody
  • CCL22_HUMAN Antibody
  • Chemokine (C C motif) ligand 22 Antibody
  • Chemokine (C-C motif) ligand 22 Antibody
  • DC/B CK Antibody
  • DC/B-CK Antibody
  • DCBCK Antibody
  • Macrophage-derived chemokine Antibody
  • MDC Antibody
  • MDC(1-69) Antibody
  • MDC(7-69) Antibody
  • MGC34554 Antibody
  • SCYA22 Antibody
  • Small inducible cytokine A22 Antibody
  • Small inducible cytokine subfamily A (Cys Cys) member 22 Antibody
  • Small inducible cytokine subfamily A (Cys-Cys), member 22 Antibody
  • Small inducible cytokine subfamily A, member 22 Antibody
  • Small-inducible cytokine A22 Antibody
  • STCP 1 Antibody
  • STCP1 Antibody
  • Stimulated T cell chemotactic protein 1 Antibody
  • Stimulated T-cell chemotactic protein 1 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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