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Anti-CBR1 Antibody

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产品名称: Anti-CBR1 Antibody
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简单介绍

Anti-CBR1 Antibody


Anti-CBR1 Antibody  的详细介绍
Name: Anti-CBR1 Antibody
See all CBR1 primary antibodies
Description: Mouse monoclonal antibody to CBR1
Specificity: This antibody detects endogenous levels of CBR1,and does not cross-react with related proteins.
Applications: WB, ICC
Dilutions: Western blotting: 1:1000
Reactivity: Human
Immunogen: Purified recombinant human CBR1 protein fragments expressed in E.coli
Host: Mouse
Clonality: Monoclonal
Isotype: IgG1
Conjugate: Unconjugated
Purification: Affinity purified
Formulation: Purified mouse monoclonal in PBS(pH 7.4)containing with 0.2% sodium azide,50% glycerol.
Storage: store at -20˚C
Function: NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2-alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S-nitrosoglutathione.
Sequence Similarities: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Cellular Location: Cytoplasm.
Database Links:
  • Entrez Gene: 873 Human
  • Omim: 114830 Human
  • SwissProt: P16152 Human
  • Unigene: 606200 Human
  • Unigene: 88778 Human
    		•
    Synonyms:
  • 15 hydroxyprostaglandin dehydrogenase [NADP+] Antibody
  • 15-hydroxyprostaglandin dehydrogenase [NADP+] Antibody
  • Carbonyl Reductase 1 Antibody
  • Carbonyl reductase [NADPH] 1 Antibody
  • CBR 1 Antibody
  • CBR1 Antibody
  • CBR1_HUMAN Antibody
  • CRN Antibody
  • NADPH dependent carbonyl reductase 1 Antibody
  • NADPH-dependent carbonyl reductase 1 Antibody
  • Prostaglandin 9 ketoreductase Antibody
  • Prostaglandin 9-ketoreductase Antibody
  • Prostaglandin E(2) 9 reductase Antibody
  • Prostaglandin-E(2) 9-reductase Antibody
  • SDR21C1 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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