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Anti-CBCP2 Antibody

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产品名称: Anti-CBCP2 Antibody
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简单介绍

Anti-CBCP2 Antibody


Anti-CBCP2 Antibody  的详细介绍
Name: Anti-CBCP2 Antibody
See all CBCP2 primary antibodies
Description: Rabbit polyclonal antibody to CBCP2
Specificity: The antibody detects endogenous levels of total CBCP2 protein.
Applications: WB, IHC
Reactivity: Human
Immunogen: Synthesized peptide derived from internal of human CBCP2.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1.0mg / ml
Formulation: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage: Store at -20?C
Function: Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK. Does not show detyrosinase or deglycylase activities from the carboxy-terminus of tubulin.
Sequence Similarities: Belongs to the peptidase M14 family.
Cellular Location: Cytoplasm > Cytosol. Cytoplasm > Cytoskeleton > Microtubule organizing center > Centrosome > Centriole. Cytoplasm > Cytoskeleton > Cilium basal body.

Colocalizes with gamma-tubulin in the centrioles and with glutamylated tubulin in the basal bodies of ciliated cells.
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