产品资料

Anti-CASP7 Antibody

如果您对该产品感兴趣的话,可以
产品名称: Anti-CASP7 Antibody
产品型号:
产品展商: 其它品牌
产品文档: 无相关文档

简单介绍

Anti-CASP7 Antibody


Anti-CASP7 Antibody  的详细介绍
Name: Anti-CASP7 Antibody
See all CASP7 primary antibodies
Description: Rabbit polyclonal antibody to CASP7
Specificity: The antibody detects endogenous level of total CASP7 protein.
Applications: WB, IHC, IF, IP
Reactivity: Human, Mouse
Immunogen: Recombinant protein of human CASP7.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antibodies were purified by affinity purification using immunogen.
Concentration: 1.0mg / ml
Formulation: Supplied at 1.0mg / mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage: Store at -20?C
Function: Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Overexpression promotes programmed cell death.
Tissue Specificity: Highly expressed in lung, skeletal muscle, liver, kidney, spleen and heart, and moderately in testis. No expression in the brain.
Sequence Similarities: Belongs to the peptidase C14A family.
Post-Translational Modification: Cleavages by granzyme B or caspase-10 generate the two active subunits. Propeptide domains can also be cleaved efficiently by caspase-3. Active heterodimers between the small subunit of caspase-7 and the large subunit of caspase-3, and vice versa, also occur.
Cellular Location: Cytoplasm.
产品留言
标题
联系人
联系电话
内容
验证码
点击换一张
注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!

沪公网安备 31011202007337号