Anti-CASP3 Antibody

点击看大图

如果您对该产品感兴趣的话,可以

产品名称: Anti-CASP3 Antibody

产品型号:

产品展商: 其它品牌

产品文档: 无相关文档

简单介绍

Anti-CASP3 Antibody

Anti-CASP3 Antibody 的详细介绍

Overview

Name:	Anti-CASP3 Antibody See all CASP3 primary antibodies
Description:	Rabbit polyclonal antibody to CASP3
Specificity:	The antibody detects endogenous level of total CASP3 protein.
Applications:	E, WB, IHC
Dilutions:	ELISA: 1:1000-1:5000 Western blotting: 1:200-1:1000 Immunohistochemistry: 1:15-1:50
Reactivity:	Human
Immunogen:	Fusion protein corresponding to a region derived from 1-269 amino acids of human caspase 3, apoptosis-related cysteine peptidase
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Predicted MW:	32kd
Formulation:	Supplied at 0.7mg / mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.3, 0.05% sodium azide and 50% glycerol.
Storage:	Store at -20?C / 1 year

Target

Background:

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.

产品留言

标题

联系人

联系电话

内容

验证码

点击换一张

注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!