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Anti-Casein Kinase 1 Alpha Antibody

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产品名称: Anti-Casein Kinase 1 Alpha Antibody
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Anti-Casein Kinase 1 Alpha Antibody


Anti-Casein Kinase 1 Alpha Antibody  的详细介绍
Name: Anti-Casein Kinase 1 Alpha Antibody
See all Casein Kinase 1 Alpha primary antibodies
Description: Chicken polyclonal antibody to Casein Kinase 1 Alpha.
Applications: WB, ICC/IF, ABC, IHC
Dilutions: WB: 1:10,000. IF: 1:500-1:1000. ABC: 1:5,000.
Reactivity: Human, Horse, Cow, Porcine, Chicken, Rat, Mouse
Immunogen: Recombinant full length CK1a (shortest isoform).
Host: Chicken
Clonality: Polyclonal
Isotype: IgY
Conjugate: Unconjugated
Purity: IgY preparation.
Product Form: Liquid
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis. May play a role in keratin cytoskeleton disassembly and thereby, it may regulate epithelial cell migration (By similarity).
Sequence Similarities: Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.
Cellular Location: Cytoplasm. Cytoplasm > Cytoskeleton > Microtubule organizing center > Centrosome. Chromosome > Centromere > Kinetochore. Nucleus speckle. Cytoplasm > Cytoskeleton > Cilium basal body.

Localizes to the centrosome in interphase cells, and to kinetochore fibers during mitosis. Also recruited to the keratin cytoskeleton.
Database Links:
  • Entrez Gene: 1452?Human
  • Entrez Gene: 93687?Mouse
  • Entrez Gene: 113927?Rat
  • Omim: 600505?Human
  • SwissProt: P48729?Human
  • SwissProt: Q8BK63?Mouse
  • SwissProt: P97633?Rat
  • Unigene: 529862?Human
  • Unigene: 712555?Human
  • Unigene: 26908?Mouse
  • Unigene: 472989?Mouse
  • Unigene: 473442?Mouse
  • Unigene: 23810?Rat
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    Synonyms:
  • Casein Kinase 1 alpha Antibody
  • Casein kinase 1 alpha 1 Antibody
  • Casein kinase I isoform alpha Antibody
  • CK1 Antibody
  • CK1A Antibody
  • CKI alpha Antibody
  • CKI-alpha Antibody
  • CKIa Antibody
  • Clock regulator kinase Antibody
  • Csnk1a1 Antibody
  • Down regulated in lung cancer Antibody
  • HLCDGP1 Antibody
  • KC1A_HUMAN Antibody
  • PRO2975 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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