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Anti-CAPG Antibody

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产品名称: Anti-CAPG Antibody
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Anti-CAPG Antibody


Anti-CAPG Antibody  的详细介绍
Name: Anti-CAPG Antibody
See all CAPG primary antibodies
Description: Rabbit polyclonal antibody to CAPG
Specificity: The antibody detects endogenous levels of total CAPG protein.
Applications: WB, IHC
Reactivity: Human, Mouse
Immunogen: Fusion protein corresponding to residues near the C terminal of human Capping protein (actin filament), gelsolin-like
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antigen affinity purification.
Concentration: 1.9mg / ml
Formulation: Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage: Store at -20?C
Function: Calcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments. May play an important role in macrophage function. May play a role in regulating cytoplasmic and/or nuclear structures through potential interactions with actin. May bind DNA.
Tissue Specificity: Macrophages and macrophage-like cells.
Sequence Similarities: Belongs to the villin/gelsolin family.
Post-Translational Modification: The N-terminus is blocked.
Cellular Location: Nucleus. Cytoplasm. Secreted. Melanosome.

Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065). Redistributes throughout the cytoplasm during mitosis and is excluded from regions containing chromosomes (By similarity).
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