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Anti-CAMTA1 Antibody

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产品名称: Anti-CAMTA1 Antibody
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简单介绍

Anti-CAMTA1 Antibody


Anti-CAMTA1 Antibody  的详细介绍
Name: Anti-CAMTA1 Antibody
See all CAMTA1 primary antibodies
Description: Rabbit polyclonal antibody to CAMTA1
Specificity: The antibody detects endogenous levels of total CAMTA1 protein.
Applications: IHC
Reactivity: Human, Mouse
Immunogen: Synthetic peptide corresponding to residues near the C terminal of human calmodulin binding transcription activator 1
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antigen affinity purification.
Concentration: 1.2mg / ml
Formulation: Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage: Store at -20?C
Function: Transcriptional activator. May act as a tumor suppressor.
Tissue Specificity: Normally expressed in non-neoplastic ***** central nervous system tissues: detected in whole brain, cerebellum, brain cortex, occipital lobe, frontal lobe, temporal lobe, putamen. Expression levels are low in oligodendroglial tumors, and are reduced by half in oligodendroglioma and astrocytoma cases with 1p loss of heterozygosity. Detected in neuroblastic-type cultured neuroblastoma cells. Expressed in heart and kidney.
Involvement in Disease: Cerebellar ataxia, non-progressive, with mental retardation: A neurodevelopmental disorder characterized by mildly delayed psychomotor development, early onset of cerebellar ataxia, and intellectual disability later in childhood and ***** life. Other features may include neonatal hypotonia, dysarthria, and dysmetria. Brain imaging in some patients shows cerebellar atrophy. Dysmorphic facial features are variable.
Sequence Similarities: Belongs to the CAMTA family.
Cellular Location: Nucleus. Cytoplasm.
Database Links:
  • Entrez Gene: 23261?Human
  • Entrez Gene: 100072?Mouse
  • Omim: 611501?Human
  • SwissProt: Q9Y6Y1?Human
  • SwissProt: A2A898?Mouse
  • Unigene: 397705?Human
  • Unigene: 671020?Human
  • Unigene: 318846?Mouse
    		•
    Synonyms:
  • Calmodulin-binding transcription activator 1 Antibody
  • CAMTA1 Antibody
  • CANPMR Antibody
  • CMTA1 Antibody
  • KIAA0833 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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