产品资料

Anti-CaMKK beta Antibody

如果您对该产品感兴趣的话,可以
产品名称: Anti-CaMKK beta Antibody
产品型号:
产品展商: 其它品牌
产品文档: 无相关文档

简单介绍

Anti-CaMKK beta Antibody


Anti-CaMKK beta Antibody  的详细介绍
Name: Anti-CaMKK beta Antibody
See all CaMKK beta primary antibodies
Description: Rabbit polyclonal antibody to CaMKK beta
Applications: WB, IF
Reactivity: Human
Immunogen: Synthetic peptide contain a sequence corresponding to a region within amino acids 1 and 15 of CaMKK beta
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Purified by antigen-affinity chromatography.
Formulation: Supplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
Storage: Store at -20˚C for long term preservation (recommended). Store at 4˚C for short term use.
Function: Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Isoform 1, isoform 2 and isoform 3 phosphorylate CAMK1 and CAMK4. Isoform 3 phosphorylates CAMK1D. Isoform 4, isoform 5 and isoform 6 lacking part of the calmodulin-binding domain are inactive. Efficiently phosphorylates 5'-AMP-activated protein kinase (AMPK) trimer, including that consisting of PRKAA1, PRKAB1 and PRKAG1. This phosphorylation is stimulated in response to Ca(2+) signals (By similarity). Seems to be involved in hippocampal activation of CREB1 (By similarity). May play a role in neurite growth. Isoform 3 may promote neurite elongation, while isoform 1 may promoter neurite branching.
Tissue Specificity: Ubiquitously expressed with higher levels in the brain. Intermediate levels are detected in spleen, prostate, thyroid and leukocytes. The lowest level is in lung.
Sequence Similarities: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Post-Translational Modification: Autophosphorylated and phosphorylated by PKA. Each isoform may show a different pattern of phosphorylation.
Cellular Location: Nucleus. Cytoplasm. Cell projection.

Predominantly nuclear in unstimulated cells (By similarity). Found in the cytoplasm and neurites after forskolin induction.
Database Links:
  • Entrez Gene: 10645 Human
  • Omim: 615002 Human
  • SwissProt: Q96RR4 Human
  • Unigene: 297343 Human
    		•
    Synonyms:
  • Calcium/calmodulin dependent protein kinase beta Antibody
  • Calcium/calmodulin dependent protein kinase kinase 2 Antibody
  • Calcium/calmodulin dependent protein kinase kinase 2 beta Antibody
  • Calcium/calmodulin dependent protein kinase kinase beta Antibody
  • Calcium/calmodulin-dependent protein kinase kinase 2 Antibody
  • Calcium/calmodulin-dependent protein kinase kinase beta Antibody
  • CaM kinase kinase beta Antibody
  • CaM KK beta Antibody
  • CaM-kinase kinase 2 Antibody
  • CaM-kinase kinase beta Antibody
  • CaM-KK 2 Antibody
  • CaM-KK beta Antibody
  • CAMKK Antibody
  • CaMKK 2 Antibody
  • CaMKK beta Antibody
  • CAMKK beta protein Antibody
  • CAMKK2 Antibody
  • CAMKKB Antibody
  • KKCC2_HUMAN Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
    产品留言
    标题
    联系人
    联系电话
    内容
    验证码
    点击换一张
    注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
    2.如有必要,请您留下您的详细联系方式!

    沪公网安备 31011202007337号