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Anti-CAMK1D Antibody

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产品名称: Anti-CAMK1D Antibody
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简单介绍

Anti-CAMK1D Antibody


Anti-CAMK1D Antibody  的详细介绍
Name: Anti-CAMK1D Antibody
See all CAMK1D primary antibodies
Description: Rabbit polyclonal antibody to CAMK1D
Specificity: The antibody detects endogenous levels of total CAMK1D protein.
Applications: IHC
Reactivity: Human
Immunogen: Fusion protein corresponding to a region derived from internal residues of human calcium / calmodulin-dependent protein kinase ID
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antigen affinity purification.
Concentration: 2.1mg / ml
Formulation: Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage: Store at -20?C
Function: Calcium/calmodulin-dependent protein kinase that operates in the calcium-triggered CaMKK-CaMK1 signaling cascade and, upon calcium influx, activates CREB-dependent gene transcription, regulates calcium-mediated granulocyte function and respiratory burst and promotes basal dendritic growth of hippocampal neurons. In neutrophil cells, required for cytokine-induced proliferative responses and activation of the respiratory burst. Activates the transcription factor CREB1 in hippocampal neuron nuclei. May play a role in apoptosis of erythroleukemia cells. In vitro, phosphorylates transcription factor CREM isoform Beta.
Tissue Specificity: Widely expressed. Highly and mostly expressed in polymorphonuclear leukocytes (neutrophilic and eosinophilic granulocytes) while little or no expression is observed in monocytes and lymphocytes.
Sequence Similarities: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.
Cellular Location: Cytoplasm. Nucleus.

Predominantly cytoplasmic. Nuclear localization increases upon activation by KCl treatment in hippocampal neurons.
Database Links:
  • Entrez Gene: 57118?Human
  • Omim: 607957?Human
  • SwissProt: Q8IU85?Human
  • Unigene: 659517?Human
  • Synonyms:
  • A630059D12Rik Antibody
  • Calcium/calmodulin dependent protein kinase ID Antibody
  • Calcium/calmodulin dependent protein kinase type 1D Antibody
  • Calcium/calmodulin-dependent protein kinase I-delta Antibody
  • Calcium/calmodulin-dependent protein kinase type 1D Antibody
  • CaM K1 Antibody
  • CaM KI delta Antibody
  • CaM kinase I delta Antibody
  • CaM kinase ID Antibody
  • CaM-KI delta Antibody
  • CAMK 1D Antibody
  • CAMK1D Antibody
  • CaMKI delta Antibody
  • CamKI like protein kinase Antibody
  • CamKI-like protein kinase Antibody
  • CaMKID Antibody
  • CKLiK Antibody
  • E030025C11Rik Antibody
  • KCC1D_HUMAN Antibody
  • OTTHUMP00000019119 Antibody
  • OTTHUMP00000019120 Antibody
  • OTTHUMP00000045030 Antibody
  • RP11 462F15.1 Antibody
  • Information: Target information shown above is from the UniProt Consortium.
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