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Anti-Calreticulin Antibody

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产品名称: Anti-Calreticulin Antibody
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Anti-Calreticulin Antibody


Anti-Calreticulin Antibody  的详细介绍
Name: Anti-Calreticulin Antibody
See all Calreticulin primary antibodies
Description: Mouse monoclonal (6C6) antibody to Calreticulin.
Applications: WB, ICC/IF, IHC
Dilutions: WB: 1:1,000-5,000. ICC/IF or IHC: 1:1,000-5,000.
Reactivity: Human, Rat, Mouse
Immunogen: Synthetic peptides VESGSLEDDWDFLPPKKI corresponding to amino acids 191-208 of human calreticulin, including the LC3 interacting region or LIR.
Host: Mouse
Clonality: Monoclonal
Clone: 6C6
Isotype: IgG1
Conjugate: Unconjugated
Purification: Immunogen affinity purified.
Concentration: 1 mg/ml
Product Form: Liquid
Formulation: Supplied in Phosphate Buffered Saline with 50% Glycerol and 5mM Sodium Azide.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis.
Tissue Specificity: Predentin and odontoblast.
Sequence Similarities: Belongs to the calreticulin family.
Cellular Location: Endoplasmic reticulum lumen. Sarcoplasmic reticulum lumen.
Database Links:
  • Entrez Gene: 811?Human
  • Entrez Gene: 12317?Mouse
  • Entrez Gene: 64202?Rat
  • Omim: 109091?Human
  • SwissProt: P27797?Human
  • SwissProt: P14211?Mouse
  • SwissProt: P18418?Rat
  • Unigene: 515162?Human
  • Unigene: 1971?Mouse
  • Unigene: 467043?Mouse
  • Unigene: 974?Rat
    		•
    Synonyms:
  • Autoantigen RO Antibody
  • CALR Antibody
  • CALR protein Antibody
  • Calregulin Antibody
  • Calreticulin Antibody
  • CALR_HUMAN Antibody
  • cC1qR Antibody
  • CRP55 Antibody
  • CRT Antibody
  • CRTC Antibody
  • Endoplasmic reticulum resident protein 60 Antibody
  • Epididymis secretory sperm binding protein Li 99n Antibody
  • ERp60 Antibody
  • FLJ26680 Antibody
  • grp60 Antibody
  • HACBP Antibody
  • HEL S 99n Antibody
  • RO Antibody
  • Sicca syndrome antigen A Antibody
  • Sicca syndrome antigen A (autoantigen Ro; calreticulin) Antibody
  • SSA Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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