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Anti-CACNA1E Antibody

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产品名称: Anti-CACNA1E Antibody
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Anti-CACNA1E Antibody


Anti-CACNA1E Antibody  的详细介绍
Name: Anti-CACNA1E Antibody
See all CACNA1E primary antibodies
Description: Rabbit polyclonal antibody to CACNA1E
Specificity: The antibody detects endogenous levels of total CACNA1E protein.
Applications: IHC
Reactivity: Human
Immunogen: Synthetic peptide corresponding to a region derived from internal residues of human calcium channel, voltage-dependent, R type, alpha 1E subunit
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antigen affinity purification.
Concentration: 1.2mg / ml
Formulation: Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage: Store at -20?C
Function: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. R-type calcium channels belong to the 'high-voltage activated' (HVA) group and are blocked by nickel, and partially by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to dihydropyridines (DHP), omega-conotoxin-GVIA (omega-CTx-GVIA), and omega-agatoxin-IVA (omega-Aga-IVA). Calcium channels containing alpha-1E subunit could be involved in the modulation of firing patterns of neurons which is important for information processing.
Tissue Specificity: Expressed in neuronal tissues and in kidney.
Sequence Similarities: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. CACNA1E subfamily.
Cellular Location: Membrane.
Synonyms:
  • alpha-1 polypeptide Antibody
  • BII Antibody
  • Brain calcium channel II Antibody
  • CAC 1E Antibody
  • CAC1E Antibody
  • CAC1E_HUMAN Antibody
  • CACH 6 Antibody
  • CACH6 Antibody
  • CACNA1E Antibody
  • Cacnl1 a6 Antibody
  • CACNL1A6 Antibody
  • Calcium channel Antibody
  • Calcium channel, L type, alpha 1 polypeptide, isoform 6 Antibody
  • calcium channel, R type Antibody
  • Cav 2.3 Antibody
  • Cav2.3 Antibody
  • Cchra 1 Antibody
  • Cchra1 Antibody
  • isoform 6 Antibody
  • L type Antibody
  • Voltage dependent R type calcium channel subunit alpha 1E Antibody
  • Voltage gated calcium channel subunit alpha Cav2.3 Antibody
  • Voltage-dependent R-type calcium channel subunit alpha-1E Antibody
  • Voltage-gated calcium channel subunit alpha Cav2.3 Antibody
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    Information: Target information shown above is from the UniProt Consortium.
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