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Anti-C5 Antibody

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产品名称: Anti-C5 Antibody
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简单介绍

Anti-C5 Antibody


Anti-C5 Antibody  的详细介绍
Name: Anti-C5 Antibody
See all C5 primary antibodies
Description: Rabbit polyclonal antibody to C5
Applications: WB, IHC
Reactivity: Human
Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1223 and 1421 of Human C5
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Purified by antigen-affinity chromatography.
Formulation: Supplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
Storage: Store at -20?C for long term preservation (recommended). Store at 4?C for short term use.
Function: Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled.
Involvement in Disease: Complement component 5 deficiency: A rare defect of the complement classical pathway associated with susceptibility to severe recurrent infections, predominantly by Neisseria gonorrhoeae or Neisseria meningitidis.
Cellular Location: Secreted.
Database Links:
  • Entrez Gene: 727?Human
  • Omim: 120900?Human
  • SwissProt: P01031?Human
  • Unigene: 494997?Human
  • Synonyms:
  • Anaphylatoxin C5a analog Antibody
  • C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4 Antibody
  • C5 Antibody
  • C5a Antibody
  • C5a anaphylatoxin Antibody
  • C5b Antibody
  • CO5_HUMAN Antibody
  • Complement C5 Antibody
  • Complement C5 alpha'' chain Antibody
  • Complement component C5 Antibody
  • CPAMD4 Antibody
  • prepro-C5 Antibody
  • Information: Target information shown above is from the UniProt Consortium.
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