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Anti-C1D Antibody

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产品名称: Anti-C1D Antibody
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简单介绍

Anti-C1D Antibody


Anti-C1D Antibody  的详细介绍
Name: Anti-C1D Antibody
See all C1D primary antibodies
Description: Goat polyclonal antibody to C1D.
Applications: ELISA, WB
Reactivity: Human
Immunogen: Synthetic peptide corresponding to Human C1D (C terminal).
Sequence: C-SKNASKVANKGKSKS
Host: Goat
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 100 µg at 0.5 mg/ml.
Product Form: Liquid
Formulation: Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Plays a role in the recruitment of the RNA exosome complex to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA; this function may include MPHOSPH6. Can activate PRKDC not only in the presence of linear DNA but also in the presence of supercoiled DNA. Can induce apoptosis in a p53/TP53 dependent manner. May regulate the TRAX/TSN complex formation. Potentiates transcriptional repression by NR1D1 and THRB (By similarity).
Tissue Specificity: Ubiquitous. Expressed at very high levels in the hippocampus, medulla oblongata, mammary gland, thyroid and salivary gland. Expressed at high levels in the fetal; lung, liver and kidney. Expressed at low levels in skeletal muscle, appendix, heart, lung and colon.
Sequence Similarities: Belongs to the C1D family.
Post-Translational Modification: Phosphorylated by PRKDC.
Cellular Location: Nucleus. Cytoplasm. Nucleus > Nucleolus.

EXOSC10 is required for nucleolar localization (PubMed:17412707). Colocalizes with TSNAX in the nucleus (PubMed:11801738).
Database Links:
  • Entrez Gene: 10438 Human
  • Omim: 606997 Human
  • SwissProt: Q13901 Human
  • Unigene: 602900 Human
  • Unigene: 697447 Human
    		•
    Synonyms:
  • 1110036E10Rik Antibody
  • AI875855 Antibody
  • C1D Antibody
  • C1D DNA binding protein Antibody
  • C1D_HUMAN Antibody
  • hC1D Antibody
  • LRP1 Antibody
  • MGC12261 Antibody
  • MGC14659 Antibody
  • MGC188504 Antibody
  • Nuclear DNA binding protein Antibody
  • Nuclear nucleic acid binding protein C1D Antibody
  • Nuclear nucleic acid-binding protein C1D Antibody
  • rCG23324 Antibody
  • RGD1560600 Antibody
  • Small unique nuclear receptor corepressor Antibody
  • SUNCOR Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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