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Anti-C14orf166 Antibody

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产品名称: Anti-C14orf166 Antibody
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简单介绍

Anti-C14orf166 Antibody


Anti-C14orf166 Antibody  的详细介绍
Name: Anti-C14orf166 Antibody
See all C14orf166 primary antibodies
Description: Rabbit polyclonal antibody to C14orf166.
Applications: WB
Dilutions: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200.
Reactivity: Human
Immunogen: Recombinant protein of human C14orf166.
Protein Length: 244
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Affinity purification.
Product Form: Liquid
Formulation: Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: RNA-binding protein involved in modulation of mRNA transcription by Polymerase II. In case of infection by influenza virus A, is involved in viral replication. Component of the tRNA-splicing ligase complex and is required for tRNA ligation (PubMed:24870230). May be required for RNA transport (PubMed:24608264).
Tissue Specificity: Widely expressed. Expressed at high level in heart and skeletal muscle. Expressed at intermediate level in liver, pancreas, fetal brain and fetal lung. Weakly expressed in ***** brain, ***** lung, placenta, fetal liver and fetal kidney. Overexpressed in many brain tumors.
Sequence Similarities: Belongs to the UPF0568 family.
Cellular Location: Nucleus. Cytoplasm > Cytosol. Cytoplasm > Perinuclear region. Cytoplasm > Cytoskeleton > Microtubule organizing center > Centrosome.

May localize at the centrosome during mitosis. Shuttles between the cytosol and the nucleus: enters into the nucleus in case of active transcription while it accumulates in cytosol when transcription level is low (PubMed:24608264).
Database Links:
  • Entrez Gene: 51637?Human
  • Omim: 610858?Human
  • SwissProt: Q9Y224?Human
  • Unigene: 534457?Human
    		•
    Synonyms:
  • C14orf166 Antibody
  • CGI 99 Antibody
  • CGI-99 Antibody
  • CGI99 Antibody
  • Chromosome 14 open reading frame 166 Antibody
  • CLE Antibody
  • CLE7 Antibody
  • CN166_HUMAN Antibody
  • Homeobox prox 1 Antibody
  • LCRP369 Antibody
  • RLL motif containing 1 Antibody
  • RLLM1 Antibody
  • UPF0568 protein C14orf166 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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