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Anti-c-TAK1 (P8) Antibody

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产品名称: Anti-c-TAK1 (P8) Antibody
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Anti-c-TAK1 (P8) Antibody


Anti-c-TAK1 (P8) Antibody  的详细介绍
Name: Anti-c-TAK1 (P8) Antibody
See all c-TAK1 primary antibodies
Description: Rabbit polyclonal antibody to c-TAK1 (P8)
Specificity: c-TAK1 (P8) pAb detects endogenous levels of C-TAK1 protein.
Applications: WB, IHC
Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide, corresponding to the N-terminal of Human c-TAK1.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Molecular Weight: ~ 87 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Function: Involved in the specific phosphorylation of microtubule-associated proteins for tau, MAP2 and MAP4. Phosphorylates CDC25C on 'Ser-216'. Regulates localization and activity of some histone deacetylases by mediating phosphorylation of HDAC7, promoting subsequent interaction between HDAC7 and 14-3-3 and export from the nucleus.
Tissue Specificity: Ubiquitous.
Sequence Similarities: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
Post-Translational Modification: Phosphorylated at Thr-211 by STK11/LKB1 in complex with STE20-related adapter-alpha (STRADA) pseudo kinase and CAB39. Phosphorylation at Thr-564 by PRKCZ/aPKC inhibits the kinase activity.
Cellular Location: Cell membrane.
Database Links:
  • Entrez Gene: 4140?Human
  • Entrez Gene: 17169?Mouse
  • Omim: 602678?Human
  • SwissProt: P27448?Human
  • SwissProt: Q03141?Mouse
  • Unigene: 35828?Human
  • Unigene: 260504?Mouse
  • Unigene: 408955?Mouse
  • Unigene: 420865?Mouse
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    Synonyms:
  • C-TAK1 Antibody
  • Cdc25C associated protein kinase 1 Antibody
  • Cdc25C-associated protein kinase 1 Antibody
  • cTAK1 Antibody
  • ELKL motif kinase 2 Antibody
  • EMK-2 Antibody
  • Emk2 Antibody
  • ETK 1 Antibody
  • KIAA4230 Antibody
  • KP78 Antibody
  • MAP microtubule affinity regulating kinase 3 Antibody
  • MAP/microtubule affinity-regulating kinase 3 Antibody
  • Mark3 Antibody
  • MARK3_HUMAN Antibody
  • Par 1a Antibody
  • PAR1A Antibody
  • Protein kinase STK10 Antibody
  • Ser/Thr protein kinase PAR-1 Antibody
  • Serine threonine protein kinase p78 Antibody
  • Serine/threonine-protein kinase p78 Antibody
  • SerThr protein kinase PAR 1 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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