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Anti-BRAP Antibody

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产品名称: Anti-BRAP Antibody
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Anti-BRAP Antibody


Anti-BRAP Antibody  的详细介绍
Name: Anti-BRAP Antibody
See all BRAP primary antibodies
Description: Mouse monoclonal antibody to BRAP
Specificity: This antibody detects endogenous levels of BRAP and does not cross-react with related proteins.
Applications: WB
Dilutions: Western blotting: 1:1000
Reactivity: Human
Immunogen: Purified recombinant human BRAP protein fragments expressed in E.coli.
Host: Mouse
Clonality: Monoclonal
Isotype: IgG1
Conjugate: Unconjugated
Purification: Affinity purified
Formulation: Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol.
Storage: store at -20˚C
Function: Negatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. Also acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto-polyubiquitination resulting in the release of inhibition of Raf/MEK complex formation. May also act as a cytoplasmic retention protein with a role in regulating nuclear transport.
Tissue Specificity: Expressed in breast epithelial cell lines.
Cellular Location: Cytoplasm.
Database Links:
  • Entrez Gene: 8315 Human
  • Omim: 604986 Human
  • SwissProt: Q7Z569 Human
    		•
    Synonyms:
  • 3010002G07Rik Antibody
  • BRAP Antibody
  • BRAP2 Antibody
  • BRCA1 associated protein Antibody
  • EC 6.3.2. Antibody
  • Galectin 2 binding protein Antibody
  • IMP Antibody
  • Impedes mitogenic signal propagation Antibody
  • Renal carcinoma antigen NY REN 63 Antibody
  • RING finger protein 52 Antibody
  • RNF52 Antibody
  • zgc:92894 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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