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Anti-BPI Antibody

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产品名称: Anti-BPI Antibody
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简单介绍

Anti-BPI Antibody


Anti-BPI Antibody  的详细介绍
Name: Anti-BPI Antibody
See all BPI primary antibodies
Description: Rabbit polyclonal antibody to BPI.
Applications: WB, IHC, IF
Dilutions: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:200.
Reactivity: Human, Mouse
Immunogen: Recombinant protein of human BPI.
Protein Length: 487
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Affinity purification.
Product Form: Liquid
Formulation: Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. Has antibacterial activity against the Gram-nagative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa.
Tissue Specificity: Restricted to cells of the myeloid series.
Sequence Similarities: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
Cellular Location: Secreted. Cytoplasmic granule membrane.

Membrane-associated in polymorphonuclear Leukocytes (PMN) granules.
Database Links:
  • Entrez Gene: 671?Human
  • Omim: 109195?Human
  • SwissProt: P17213?Human
  • Unigene: 529019?Human
    		•
    Synonyms:
  • Bactericidal permeability-increasing protein Antibody
  • bactericidal/permeability-increasing protein Antibody
  • BPI Antibody
  • BPI fold containing family D, member 1 Antibody
  • BPIFD1 Antibody
  • CAP 57 Antibody
  • rBPI Antibody
  • recombinant BPI holoprotein, rBPI Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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