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Anti-BMP4 Antibody

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产品名称: Anti-BMP4 Antibody
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简单介绍

Anti-BMP4 Antibody


Anti-BMP4 Antibody  的详细介绍
Name: Anti-BMP4 Antibody
See all BMP4 primary antibodies
Description: Rabbit polyclonal antibody to BMP4
Specificity: The antibody detects endogenous levels of total BMP4 protein.
Applications: IHC, WB
Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide of human BMP4
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antigen affinity purification
Concentration: 0.5mg / ml
Formulation: Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Storage: Store at -20?C
Function: Induces cartilage and bone formation. Also act in mesoderm induction, tooth development, limb formation and fracture repair. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity).
Tissue Specificity: Expressed in the lung and lower levels seen in the kidney. Present also in normal and neoplastic prostate tissues, and prostate cancer cell lines.
Involvement in Disease: Microphthalmia, syndromic, 6: A disease characterized by microphthalmia/anophthalmia associated with facial, genital, skeletal, neurologic and endocrine anomalies. Microphthalmia is a disorder of eye formation, ranging from small size of a single eye to complete bilateral absence of ocular tissues (anophthalmia). In many cases, microphthalmia/anophthalmia occurs in association with syndromes that include non-ocular abnormalities.

Non-syndromic orofacial cleft 11: A birth defect consisting of cleft lips with or without cleft palate. Cleft lips are associated with cleft palate in two-third of cases. A cleft lip can occur on one or both sides and range in severity from a simple notch in the upper lip to a complete opening in the lip extending into the floor of the nostril and involving the upper gum.
Sequence Similarities: Belongs to the TGF-beta family.
Cellular Location: Secreted > Extracellular space > Extracellular matrix.
Database Links:
  • Entrez Gene: 652?Human
  • Entrez Gene: 12159?Mouse
  • Entrez Gene: 25296?Rat
  • Omim: 112262?Human
  • SwissProt: P12644?Human
  • SwissProt: P21275?Mouse
  • SwissProt: Q06826?Rat
  • Unigene: 68879?Human
  • Unigene: 6813?Mouse
  • Unigene: 10318?Rat
    		•
    Synonyms:
  • zgc:100779 Antibody
  • BMP 2B Antibody
  • BMP 4 Antibody
  • BMP-2B Antibody
  • BMP-4 Antibody
  • BMP2B Antibody
  • BMP2B1 Antibody
  • BMP4 Antibody
  • BMP4_HUMAN Antibody
  • BOMPR4A Antibody
  • Bone morphogenetic protein 2B Antibody
  • Bone morphogenetic protein 4 Antibody
  • DVR4 Antibody
  • MCOPS6 Antibody
  • MGC100779 Antibody
  • OFC11 Antibody
  • OTTMUSP00000021065 Antibody
  • OTTMUSP00000021066 Antibody
  • zbmp-4 Antibody
  • ZYME Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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