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Anti-BMP2 Antibody

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产品名称: Anti-BMP2 Antibody
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简单介绍

Anti-BMP2 Antibody


Anti-BMP2 Antibody  的详细介绍
Name: Anti-BMP2 Antibody
See all BMP2 primary antibodies
Description: Rabbit polyclonal antibody to BMP2
Applications: Dot blot, ELISA, WB, ICC/IF, IHC-Fr, IHC-P, IP, WB
Dilutions: DB: 1:2,000; ELISA: 1:2,000; Immunocytochemistry: 1:200; Immunofluorescence: 1:200; Immunohistochemistry: 1:200-1:500; Immunoprecipitation: 1:200; Western Blot: 1:500-1:1000
Reactivity: Human, Monkey, Mouse, Rat
Immunogen: Synthetic peptide corresponding to Mouse BMP2 amino acid region 45-60 conjugated to Keyhole Limpet Haemocyanin (KLH).
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Concentration: 0.73 μg/μl in antibody stabilization buffer
Storage: -20?C for long term storage
Function: Induces cartilage and bone formation. Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3-EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4.
Sequence Similarities: Belongs to the TGF-beta family.
Cellular Location: Secreted.
Database Links:
  • Entrez Gene: 650?Human
  • Entrez Gene: 12156?Mouse
  • Entrez Gene: 29373?Rat
  • Omim: 112261?Human
  • SwissProt: P12643?Human
  • SwissProt: P21274?Mouse
  • SwissProt: P49001?Rat
  • Unigene: 73853?Human
  • Unigene: 103205?Mouse
  • Unigene: 90931?Rat
    		•
    Synonyms:
  • BDA2 Antibody
  • BMP-2 Antibody
  • BMP-2A Antibody
  • BMP2 Antibody
  • BMP2A Antibody
  • BMP2_HUMAN Antibody
  • Bone morphogenetic protein 2 Antibody
  • Bone morphogenetic protein 2A Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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