产品资料

Anti-BMP-2 Antibody

如果您对该产品感兴趣的话,可以
产品名称: Anti-BMP-2 Antibody
产品型号:
产品展商: 其它品牌
产品文档: 无相关文档

简单介绍

Anti-BMP-2 Antibody


Anti-BMP-2 Antibody  的详细介绍
Name: Anti-BMP-2 Antibody
See all BMP-2 primary antibodies
Description: Rabbit polyclonal antibody to BMP-2
Specificity: BMP-2 Polyclonal Antibody detects endogenous levels of BMP-2 protein.
Applications: WB, IHC, ELISA
Reactivity: Human, Mouse, Rat
Immunogen: Synthesized peptide derived from the Internal region of human BMP-2.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1mg / ml
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage: Store at -20?C / 1 year
Function: Induces cartilage and bone formation (PubMed:3201241). Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3-EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4 (PubMed:24362451).
Tissue Specificity: Particularly abundant in lung, spleen and colon and in low but significant levels in heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, ovary and small intestine.
Sequence Similarities: Belongs to the TGF-beta family.
Cellular Location: Secreted.
Database Links:
  • Entrez Gene: 650?Human
  • Entrez Gene: 12156?Mouse
  • Entrez Gene: 29373?Rat
  • Omim: 112261?Human
  • SwissProt: P12643?Human
  • SwissProt: P21274?Mouse
  • SwissProt: P49001?Rat
  • Unigene: 73853?Human
  • Unigene: 103205?Mouse
  • Unigene: 90931?Rat
    		•
    Synonyms:
  • BDA2 Antibody
  • BMP-2 Antibody
  • BMP-2A Antibody
  • BMP2 Antibody
  • BMP2A Antibody
  • BMP2_HUMAN Antibody
  • Bone morphogenetic protein 2 Antibody
  • Bone morphogenetic protein 2A Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
    产品留言
    标题
    联系人
    联系电话
    内容
    验证码
    点击换一张
    注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
    2.如有必要,请您留下您的详细联系方式!

    沪公网安备 31011202007337号