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Anti-bisphosphoglycerate mutase Antibody

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产品名称: Anti-bisphosphoglycerate mutase Antibody
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Anti-bisphosphoglycerate mutase Antibody


Anti-bisphosphoglycerate mutase Antibody  的详细介绍
Name: Anti-bisphosphoglycerate mutase Antibody
See all bisphosphoglycerate mutase primary antibodies
Description: Rabbit polyclonal antibody to bisphosphoglycerate mutase
Applications: WB, IF
Reactivity: Human
Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 216 of Human BPGM
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Purified by antigen-affinity chromatography.
Formulation: Supplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
Storage: Store at -20˚C for long term preservation (recommended). Store at 4˚C for short term use.
Function: Plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of its allosteric effector 2,3-bisphosphoglycerate (2,3-BPG). Also exhibits mutase (EC 5.4.2.1) activity.
Tissue Specificity: Expressed in red blood cells. Expressed in non-erythroid cells of the placenta; present in the syncytiotrophoblast layer of the placental villi at the feto-maternal interface (at protein level).
Involvement in Disease: Bisphosphoglycerate mutase deficiency: A disease characterized by hemolytic anemia, splenomegaly, cholelithiasis and cholecystitis.
Sequence Similarities: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Post-Translational Modification: Glycation of Lys-159 in diabetic patients inactivates the enzyme.
Database Links:
  • Entrez Gene: 669 Human
  • Omim: 613896 Human
  • SwissProt: P07738 Human
  • Unigene: 198365 Human
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    Synonyms:
  • 2 Antibody
  • 2,3-bisphosphoglycerate mutase Antibody
  • 2,3-bisphosphoglycerate mutase, erythrocyte Antibody
  • 2,3-bisphosphoglycerate synthase Antibody
  • 2,3-diphosphoglycerate mutase Antibody
  • 3-bisphosphoglycerate mutase Antibody
  • 3-bisphosphoglycerate synthase Antibody
  • 3-diphosphoglycerate mutase Antibody
  • Ab2 098 Antibody
  • AI323730 Antibody
  • AL022789 Antibody
  • Bisphosphoglycerate mutase Antibody
  • BPG dependent PGAM Antibody
  • BPG-dependent PGAM Antibody
  • BPGM Antibody
  • C86192 Antibody
  • DPGM Antibody
  • erythrocyte Antibody
  • Erythrocyte 2,3 bisphosphoglycerate mutase Antibody
  • PMGE_HUMAN Antibody
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    Information: Target information shown above is from the UniProt Consortium.
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