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Anti-Bim Antibody

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产品名称: Anti-Bim Antibody
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简单介绍

Anti-Bim Antibody


Anti-Bim Antibody  的详细介绍
Name: Anti-Bim Antibody
See all Bim primary antibodies
Description: Rabbit polyclonal antibody to Bim
Applications: E, WB, ICC
Reactivity: Human, Mouse, Rat
Immunogen: Raised against a peptide corresponding to amino acids near the center of human Bim. The sequence is identical to that of mouse and rat.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Affinity chromatography purified via peptide column
Formulation: Supplied in PBS containing 0.02% sodium azide.
Storage: Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Function: Induces apoptosis and anoikis.
Tissue Specificity: Widely expressed.
Sequence Similarities: Belongs to the Bcl-2 family.
Post-Translational Modification: Phosphorylation at Ser-65 by MAPK1/MAPK3 leads interaction with TRIM2 and ubiquitination, followed by proteasomal degradation. Deubiquitination catalyzed by USP27X stabilizes the protein.
Cellular Location: Membrane. Mitochondrion.

Associated with intracytoplasmic membranes.
Database Links:
  • Entrez Gene: 10018 Human
  • Entrez Gene: 12125 Mouse
  • Entrez Gene: 64547 Rat
  • Omim: 603827 Human
  • SwissProt: O43521 Human
  • SwissProt: O54918 Mouse
  • SwissProt: O88498 Rat
  • Unigene: 469658 Human
  • Unigene: 141083 Mouse
  • Unigene: 453214 Mouse
  • Unigene: 82709 Rat
    		•
    Synonyms:
  • BCL2 like 11 Antibody
  • B2L11_HUMAN Antibody
  • BAM Antibody
  • Bcl 2 interacting protein Bim Antibody
  • Bcl 2 related ovarian death agonist Antibody
  • Bcl-2-like protein 11 Antibody
  • BCL2 interacting mediator of cell death Antibody
  • BCL2 like 11 (apoptosis facilitator) Antibody
  • BCL2 like protein 11 Antibody
  • Bcl2-interacting mediator of cell death Antibody
  • Bcl2-L-11 Antibody
  • Bcl2l11 Antibody
  • Bim Antibody
  • BIM alpha6 Antibody
  • BIM beta6 Antibody
  • BIM beta7 Antibody
  • BimEL Antibody
  • BimL Antibody
  • BOD Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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