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Anti-BIK (M27) Antibody

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产品名称: Anti-BIK (M27) Antibody
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简单介绍

Anti-BIK (M27) Antibody


Anti-BIK (M27) Antibody  的详细介绍
Name: Anti-BIK (M27) Antibody
See all BIK primary antibodies
Description: Rabbit polyclonal antibody to BIK (M27)
Specificity: BIK (M27)pAb detects endogenous levels of BIK protein
Applications: WB, IHC, IF
Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide, corresponding to the N-terminal of Human BIK.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Molecular Weight: ~ 23 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Function: Accelerates programmed cell death. Association to the apoptosis repressors Bcl-X(L), BHRF1, Bcl-2 or its adenovirus homolog E1B 19k protein suppresses this death-promoting activity. Does not interact with BAX.
Post-Translational Modification: Proteolytically cleaved by RHBDL4/RHBDD1. RHBDL4/RHBDD1-induced cleavage is a necessary step prior its degradation by the proteosome-dependent mechanism.
Cellular Location: Endomembrane system. Mitochondrion membrane.

Around the nuclear envelope, and in cytoplasmic membranes.
Database Links:
  • Entrez Gene: 638?Human
  • Entrez Gene: 12124?Mouse
  • Entrez Gene: 114496?Rat
  • Omim: 603392?Human
  • SwissProt: Q13323?Human
  • SwissProt: O70337?Mouse
  • Unigene: 475055?Human
  • Synonyms:
  • Apoptosis inducer NBK Antibody
  • BBC1 Antibody
  • Bcl-2-interacting killer Antibody
  • BCL2 interacting killer Antibody
  • bhikhari Antibody
  • Bik Antibody
  • Bik-like killer protein Antibody
  • BIK_HUMAN Antibody
  • BIP 1 Antibody
  • BiP1 Antibody
  • BP 4 Antibody
  • BP4 Antibody
  • cb 60 Antibody
  • NBK Antibody
  • Information: Target information shown above is from the UniProt Consortium.
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