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Anti-Bid Antibody

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产品名称: Anti-Bid Antibody
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简单介绍

Anti-Bid Antibody


Anti-Bid Antibody  的详细介绍
Name: Anti-Bid Antibody
See all Bid primary antibodies
Description: Rabbit polyclonal antibody to Bid
Applications: E, WB, IHC
Reactivity: Human, Mouse
Immunogen: Raised against a peptide corresponding to 14 amino acids near the carboxy terminus of human Bid.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Ion exchange chromatography purified
Formulation: Supplied in PBS containing 0.02% sodium azide.
Storage: Can be stored at -20?C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Function: Induces caspases and apoptosis. Counters the protective effect of Bcl-2. The major proteolytic product p15 BID allows the release of cytochrome c.
Post-Translational Modification: TNF-alpha induces a caspase-mediated cleavage of p22 BID into a major p15 and minor p13 and p11 products.
Cellular Location: Cytoplasm. Mitochondrion membrane.

When uncleaved, it is predominantly cytoplasmic. p15 BID translocates to mitochondria as an integral membrane protein. p13 and p22 BID are associated with the mitochondrial membrane.
Database Links:
  • Entrez Gene: 637?Human
  • Entrez Gene: 12122?Mouse
  • Omim: 601997?Human
  • SwissProt: P55957?Human
  • SwissProt: P70444?Mouse
  • Unigene: 591054?Human
  • Unigene: 235081?Mouse
    		•
    Synonyms:
  • Apoptic death agonist Antibody
  • Apoptotic death agonist BID Antibody
  • BH3 interacting domain death agonist Antibody
  • BH3 interacting domain death agonist p11 Antibody
  • BH3 interacting domain death agonist p13 Antibody
  • BH3 interacting domain death agonist p15 Antibody
  • BH3-interacting domain death agonist p11 Antibody
  • Bid Antibody
  • BID isoform ES(1b) Antibody
  • BID isoform L(2) Antibody
  • BID isoform Si6 Antibody
  • BID_HUMAN Antibody
  • Desmocollin type 4 Antibody
  • FP497 Antibody
  • Human BID coding sequence Antibody
  • MGC15319 Antibody
  • MGC42355 Antibody
  • p11 BID Antibody
  • p13 BID Antibody
  • p15 BID Antibody
  • p22 BID Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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