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Anti-BID Antibody

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产品名称: Anti-BID Antibody
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简单介绍

Anti-BID Antibody


Anti-BID Antibody  的详细介绍
Name: Anti-BID Antibody
See all BID primary antibodies
Description: Rabbit polyclonal antibody to BID
Specificity: BID pAb detects endogenous levels of Bid protein.
Applications: WB, IHC
Reactivity: Human, Mouse, Rat
Immunogen: Recombinant full length Human BID.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Molecular Weight: ~ 22 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form: 1mg/ml in PBS?with?0.1%?Sodium?Azide,?50%?Glycerol.
Function: The major proteolytic product p15 BID allows the release of cytochrome c (By similarity). Isoform 1, isoform 2 and isoform 4 induce ICE-like proteases and apoptosis. Isoform 3 does not induce apoptosis. Counters the protective effect of Bcl-2.
Tissue Specificity: Isoform 2 and isoform 3 are expressed in spleen, bone marrow, cerebral and cerebellar cortex. Isoform 2 is expressed in spleen, pancreas and placenta (at protein level). Isoform 3 is expressed in lung, pancreas and spleen (at protein level). Isoform 4 is expressed in lung and pancreas (at protein level).
Post-Translational Modification: TNF-alpha induces a caspase-mediated cleavage of p22 BID into a major p15 and minor p13 and p11 products.
Cellular Location: Cytoplasm. Mitochondrion membrane.

When uncleaved, it is predominantly cytoplasmic.
Database Links:
  • Entrez Gene: 637?Human
  • Entrez Gene: 12122?Mouse
  • Entrez Gene: 64625?Rat
  • Omim: 601997?Human
  • SwissProt: P55957?Human
  • SwissProt: P70444?Mouse
  • SwissProt: Q9JLT6?Rat
  • Unigene: 591054?Human
  • Unigene: 235081?Mouse
  • Unigene: 31142?Rat
    		•
    Synonyms:
  • Apoptic death agonist Antibody
  • Apoptotic death agonist BID Antibody
  • BH3 interacting domain death agonist Antibody
  • BH3 interacting domain death agonist p11 Antibody
  • BH3 interacting domain death agonist p13 Antibody
  • BH3 interacting domain death agonist p15 Antibody
  • BH3-interacting domain death agonist p11 Antibody
  • Bid Antibody
  • BID isoform ES(1b) Antibody
  • BID isoform L(2) Antibody
  • BID isoform Si6 Antibody
  • BID_HUMAN Antibody
  • Desmocollin type 4 Antibody
  • FP497 Antibody
  • Human BID coding sequence Antibody
  • MGC15319 Antibody
  • MGC42355 Antibody
  • p11 BID Antibody
  • p13 BID Antibody
  • p15 BID Antibody
  • p22 BID Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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