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Anti-BCL3 Antibody

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产品名称: Anti-BCL3 Antibody
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简单介绍

Anti-BCL3 Antibody


Anti-BCL3 Antibody  的详细介绍
Name: Anti-BCL3 Antibody
See all BCL3 primary antibodies
Description: Rabbit polyclonal antibody to BCL3
Specificity: The antibody detects endogenous levels of total BCL3 protein.
Applications: WB, IHC
Reactivity: Human, Mouse
Immunogen: Synthetic peptide corresponding to residues near the N terminal of human B-cell CLL / lymphoma 3
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antigen affinity purification.
Concentration: 1mg / ml
Formulation: Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage: Store at -20?C
Function: Contributes to the regulation of transcriptional activation of NF-kappa-B target genes. In the cytoplasm, inhibits the nuclear translocation of the NF-kappa-B p50 subunit. In the nucleus, acts as transcriptional activator that promotes transcription of NF-kappa-B target genes. Contributes to the regulation of cell proliferation (By similarity).
Post-Translational Modification: Polyubiquitinated. Ubiquitination via 'Lys-63'-linked ubiquitin chains is required for nuclear accumulation. Deubiquitinated by CYLD, which acts on 'Lys-63'-linked ubiquitin chains. Deubiquitination by CYLD prevents nuclear accumulation (By similarity).
Cellular Location: Nucleus. Cytoplasm. Cytoplasm > Perinuclear region.

Ubiquitination via 'Lys-63'-linked ubiquitin chains is required for nuclear accumulation.
Database Links:
  • Entrez Gene: 602?Human
  • Entrez Gene: 12051?Mouse
  • Omim: 109560?Human
  • SwissProt: P20749?Human
  • SwissProt: Q9Z2F6?Mouse
  • Unigene: 31210?Human
    		•
    Synonyms:
  • B cell CLL/lymphoma 3 Antibody
  • B cell leukemia/lymphoma 3 Antibody
  • B cell lymphoma 3 encoded protein Antibody
  • B-cell lymphoma 3 protein Antibody
  • Bcl 3 Antibody
  • BCL 4 Antibody
  • BCL-3 Antibody
  • Bcl3 Antibody
  • BCL3_HUMAN Antibody
  • BCL4 Antibody
  • Chronic lymphatic leukemia protein Antibody
  • D19S37 Antibody
  • Protein Bcl 3 Antibody
  • Proto-oncogene BCL3 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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