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Anti-BCL2L2 Antibody

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产品名称: Anti-BCL2L2 Antibody
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简单介绍

Anti-BCL2L2 Antibody


Anti-BCL2L2 Antibody  的详细介绍
Name: Anti-BCL2L2 Antibody
See all BCL2L2 primary antibodies
Description: Rabbit polyclonal antibody to BCL2L2
Specificity: The antibody detects endogenous level of total BCL2L2 protein.
Applications: WB, IHC
Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein of human BCL2L2.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antibodies were purified by affinity purification using immunogen.
Concentration: 1.0mg / ml
Formulation: Supplied at 1.0mg / mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage: Store at -20?C
Function: Promotes cell survival. Blocks dexamethasone-induced apoptosis. Mediates survival of postmitotic Sertoli cells by suppressing death-promoting activity of BAX.
Tissue Specificity: Expressed (at protein level) in a wide range of tissues with highest levels in brain, spinal cord, testis, pancreas, heart, spleen and mammary glands. Moderate levels found in thymus, ovary and small intestine. Not detected in salivary gland, muscle or liver. Also expressed in cell lines of myeloid, fibroblast and epithelial origin. Not detected in most lymphoid cell lines.
Sequence Similarities: Belongs to the Bcl-2 family.
Cellular Location: Mitochondrion membrane.

Loosely associated with the mitochondrial membrane in healthy cells. During apoptosis, tightly bound to the membrane.
Database Links:
  • Entrez Gene: 599?Human
  • Entrez Gene: 12050?Mouse
  • Entrez Gene: 60434?Rat
  • Omim: 601931?Human
  • SwissProt: Q92843?Human
  • SwissProt: P70345?Mouse
  • Unigene: 410026?Human
  • Unigene: 397611?Mouse
  • Unigene: 6967?Mouse
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    Synonyms:
  • Apoptosis regulator BCL W Antibody
  • Apoptosis regulator Bcl-W Antibody
  • B2CL2_HUMAN Antibody
  • BCL 2 Like 2 Antibody
  • Bcl 2 like 2 protein Antibody
  • Bcl 2L2 Antibody
  • BCL W Antibody
  • Bcl-2-like protein 2 Antibody
  • Bcl2 L2 Antibody
  • BCL2 like 2 Antibody
  • BCL2 like 2 protein Antibody
  • Bcl2-L-2 Antibody
  • Bcl2L2 Antibody
  • BCLW Antibody
  • KIAA0271 Antibody
  • PPP1R51 Antibody
  • Protein phosphatase 1 regulatory subunit 51 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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