产品资料

Anti-BCL11A Antibody

如果您对该产品感兴趣的话,可以
产品名称: Anti-BCL11A Antibody
产品型号:
产品展商: 其它品牌
产品文档: 无相关文档

简单介绍

Anti-BCL11A Antibody


Anti-BCL11A Antibody  的详细介绍
Name: Anti-BCL11A Antibody
See all BCL11A primary antibodies
Description: Rabbit polyclonal antibody to BCL11A.
Applications: WB, IHC
Dilutions: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200.
Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein of human BCL11A.
Protein Length: 835 (773)
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Affinity purification.
Product Form: Liquid
Formulation: Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Transcription factor associated with the BAF SWI/SNF chromatin remodeling complex (By similarity). Repressor of fetal hemoglobin (HbF) level (PubMed:26375765). Involved in brain development (PubMed:27453576). Functions as a myeloid and B-cell proto-oncogene. May play important roles in leukemogenesis and hematopoiesis. Essential factor in lymphopoiesis required for B-cell formation in fetal liver. May function as a modulator of the transcriptional repression activity of ARP1 (By similarity).
Tissue Specificity: Expressed at high levels in brain, spleen thymus, bone marrow and testis. Expressed in CD34-positive myeloid precursor cells, B-cells, monocytes and megakaryocytes. Expression is tightly regulated during B-cell development.
Involvement in Disease: Intellectual developmental disorder with persistence of fetal hemoglobin: An autosomal dominant disorder characterized by delayed psychomotor development, intellectual disability, variable dysmorphic features, including microcephaly, downslanting palpebral fissures, strabismus, and external ear abnormalities, and asymptomatic persistence of fetal hemoglobin.
Post-Translational Modification: Sumoylated with SUMO1.
Cellular Location: Cytoplasm. Nucleus.

Associates with the nuclear body. Colocalizes with SUMO1 and SENP2 in nuclear speckles (By similarity).
Database Links:
  • Entrez Gene: 53335?Human
  • Entrez Gene: 14025?Mouse
  • Entrez Gene: 305589?Rat
  • Omim: 606557?Human
  • SwissProt: Q9H165?Human
  • SwissProt: Q9QYE3?Mouse
  • Unigene: 370549?Human
  • Unigene: 441102?Mouse
  • Unigene: 471050?Mouse
  • Unigene: 53687?Mouse
  • Unigene: 88824?Mouse
  • Unigene: 16729?Rat
    		•
    Synonyms:
  • 2810047E18Rik Antibody
  • B cell CLL/lymphoma 11A (zinc finger protein) Antibody
  • B cell CLL/lymphoma 11A (zinc finger protein) isoform 2 Antibody
  • B-cell CLL/lymphoma 11A Antibody
  • B-cell lymphoma/leukemia 11A Antibody
  • BC11A_HUMAN Antibody
  • BCL-11A Antibody
  • BCL11A Antibody
  • BCL11A B cell CLL/lymphoma 11A (zinc finger protein) isoform 1 Antibody
  • BCL11A L Antibody
  • BCL11A S Antibody
  • BCL11A XL Antibody
  • BCL11a-M Antibody
  • BCL11AL Antibody
  • BCL11AS Antibody
  • BCL11AXL Antibody
  • C2H2 type zinc finger protein Antibody
  • COUP TF interacting protein 1 Antibody
  • COUP-TF-interacting protein 1 Antibody
  • Ctip1 Antibody
  • CTIP1, mouse, homolog of Antibody
  • D930021L15Rik Antibody
  • Ecotropic viral integration site 9 Antibody
  • Ecotropic viral integration site 9 homolog Antibody
  • Ecotropic viral integration site 9 protein Antibody
  • Ecotropic viral integration site 9 protein homolog Antibody
  • EVI-9 Antibody
  • Evi9 Antibody
  • Evi9, mouse, homolog of Antibody
  • FLJ10173 Antibody
  • FLJ34997 Antibody
  • HBFQTL5 Antibody
  • KIAA1809 Antibody
  • mKIAA1809 Antibody
  • OTTHUMP00000159788 Antibody
  • OTTHUMP00000159789 Antibody
  • OTTHUMP00000201250 Antibody
  • OTTHUMP00000202084 Antibody
  • Zinc finger protein 856 Antibody
  • ZNF856 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
    产品留言
    标题
    联系人
    联系电话
    内容
    验证码
    点击换一张
    注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
    2.如有必要,请您留下您的详细联系方式!

    沪公网安备 31011202007337号