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Antibodies
Anti-BAP31 Antibody
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产品名称:
Anti-BAP31 Antibody
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简单介绍
Anti-BAP31
Antibody
Anti-BAP31 Antibody
的详细介绍
Overview
Name:
Anti-BAP31
Antibody
See all BAP31 primary antibodies
Description:
Rabbit polyclonal antibody to BAP31
Specificity:
BAP31 Polyclonal Antibody detects endogenous levels of BAP31 protein.
Applications:
WB, ELISA
Reactivity:
Human, Mouse, Rat
Immunogen:
Synthesized peptide derived from the Internal region of human BAP31.
Host:
Rabbit
Clonality:
Polyclonal
Conjugate:
Unconjugated
Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:
1mg / ml
Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage:
Store at -20˚C / 1 year
Target
Function:
Functions as a chaperone protein. Is one of the most abundant endoplasmic reticulum (ER) proteins. Plays a role in the export of secreted proteins in the ER, the recognition of abnormally folded protein and their targeting to the ER associated-degradation (ERAD). Also serves as a cargo receptor for the export of transmembrane proteins. May be involved in CASP8-mediated apoptosis.
Tissue Specificity:
Ubiquitous. Highly expressed in neurons and discrete endocrine cells.
Involvement in Disease:
Deafness, dystonia, and cerebral hypomyelination: An X-linked recessive mental retardation syndrome characterized by almost no psychomotor development, dysmorphic facial features, sensorineural deafness, dystonia, pyramidal signs, and hypomyelination on brain imaging.
Sequence Similarities:
Belongs to the BCAP29/BCAP31 family.
Post-Translational Modification:
Cleaved by CASP8 and other caspases.
Cellular Location:
Endoplasmic reticulum membrane. Endoplasmic reticulum-Golgi intermediate compartment membrane.
May shuttle between the ER and the intermediate compartment/cis-Golgi complex.
Database Links:
Entrez Gene: 10134 Human
Entrez Gene: 27061 Mouse
Entrez Gene: 293852 Rat
Omim: 300398 Human
SwissProt: P51572 Human
SwissProt: Q61335 Mouse
Unigene: 522817 Human
Unigene: 17 Mouse
Unigene: 96419 Rat
Synonyms:
6C6 AG Antibody
6C6 AG tumor associated antigen Antibody
6C6-AG tumor-associated antigen Antibody
6C6AG Antibody
6C6AG tumor associated antigen Antibody
Accessory protein BAP 31 Antibody
Accessory protein BAP31 Antibody
B cell receptor associated protein 31 Antibody
B-cell receptor-associated protein 31 Antibody
BA31 Antibody
BAP 31 Antibody
BAP31 Antibody
BAP31_HUMAN Antibody
BCAP 31 Antibody
BCAP31 Antibody
BCR associated protein Bap 31 Antibody
BCR associated protein Bap31 Antibody
BCR-associated protein 31 Antibody
CDM Antibody
CDM protein Antibody
DXS1357E Antibody
MS950 Antibody
p28 Antibody
p28 Bap31 Antibody
Protein CDM Antibody
RP23-329M9.5 Antibody
Information:
Target information shown above is from the UniProt Consortium.
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