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Anti-BAIAP2 Antibody

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产品名称: Anti-BAIAP2 Antibody
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简单介绍

Anti-BAIAP2 Antibody


Anti-BAIAP2 Antibody  的详细介绍
Name: Anti-BAIAP2 Antibody
See all BAIAP2 primary antibodies
Description: Goat polyclonal antibody to BAIAP2.
Applications: ELISA, WB, IHC
Reactivity: Human
Immunogen: Synthetic peptide corresponding to Human BAIAP2 (C terminal).
Sequence: C-SGSGTLVSTV
Host: Goat
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 100 μg at 0.5 mg/ml.
Product Form: Liquid
Formulation: Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Adapter protein that links membrane-bound small G-proteins to cytoplasmic effector proteins. Necessary for CDC42-mediated reorganization of the actin cytoskeleton and for RAC1-mediated membrane ruffling. Involved in the regulation of the actin cytoskeleton by WASF family members and the Arp2/3 complex. Plays a role in neurite growth. Acts syngeristically with ENAH to promote filipodia formation. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection. Participates in actin bundling when associated with EPS8, promoting filopodial protrusions.
Tissue Specificity: Isoform 1 and isoform 4 are expressed almost exclusively in brain. Isoform 4 is barely detectable in placenta, prostate and testis. A short isoform is ubiquitous, with the highest expression in liver, prostate, testis and placenta.
Post-Translational Modification: Phosphorylated on tyrosine residues by INSR in response to insulin treatment.
Cellular Location: Cytoplasm. Membrane. Cell projection > Filopodium. Cell projection > Ruffle. Cytoplasm > Cytoskeleton.

Detected throughout the cytoplasm in the absence of specific binding partners. Detected in filopodia and close to membrane ruffles. Recruited to actin pedestals that are formed upon infection by bacteria at bacterial attachment sites.
Database Links:
  • Entrez Gene: 10458?Human
  • GenBank: NP_006331.1?Human
  • Omim: 605475?Human
  • SwissProt: Q9UQB8?Human
  • Unigene: 128316?Human
    		•
    Synonyms:
  • BAI-associated protein 2 Antibody
  • BAI1 associated protein 2 Antibody
  • BAI1-associated protein 2 Antibody
  • BAIAP 2 Antibody
  • BAIAP2 Antibody
  • BAIP2_HUMAN Antibody
  • BAP2 Antibody
  • Brain-specific angiogenesis inhibitor 1-associated protein 2 Antibody
  • Fas ligand-associated factor 3 Antibody
  • FLAF3 Antibody
  • Insulin receptor substrate p53 Antibody
  • Insulin receptor substrate p53/p58 Antibody
  • Insulin receptor substrate protein of 53 kDa Antibody
  • IRS-58 Antibody
  • IRSp53 Antibody
  • IRSp53/58 Antibody
  • Protein BAP2 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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